DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and CG18557

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_608721.1	Gene:	CG18557 / 33483	FlyBaseID:	FBgn0031470	Length:	343	Species:	Drosophila melanogaster

Alignment Length:	260	Identity:	109/260 - (41%)
Similarity:	149/260 - (57%)	Gaps:	10/260 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 SCGMSNANGLQMVEGITIDQARPAQYPWAVAIFHN-GQYLAGGSLIQPNVVLTVAHRVI--TIET 293
            :||.||.|||.......:|||:|.::||.||:..| ..:...|:|:..|:|:|.||.::  || .
  Fly    70 NCGKSNPNGLGGTVEEVVDQAKPNEFPWTVALMQNLINFFGAGTLVTENIVITAAHLMLDKTI-N 133

  Fly   294 ELVVRAGDWDLK--SDREIFLSEQREVERAVIHEGFDFKSGANNLALLFLNSPFKLNDHIRTICL 356
            :..:..|.||||  :.:.|   :.|...|.|.|..|:..:||||:||:.|.:.|.:...|..||.
  Fly   134 DFGIIGGAWDLKQLAGKTI---QWRTATRIVSHPDFNKMTGANNIALIVLETSFVMKPPIGPICW 195

  Fly   357 PTPNKSFAGRRCTVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNIIC 421
            ||...||...||.|||||:..:..:.||...||:.|.:|:|:.||..||.|.....|:|...|:|
  Fly   196 PTSGVSFDRERCLVAGWGRPDFLAKNYSYKQKKIDLPIVSRSDCESLLRRTAFVQSFQLDPTILC 260

  Fly   422 AGGELGRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPAIYTEVSKFTNWITEKL 486
            ||||.|||.|.|||||.|.|.|.| :..:||..||||.|..||.|.:||:||.:|....||.::|
  Fly   261 AGGERGRDACIGDGGSPLMCPIPG-HPAIYELVGIVNSGFSCGLENVPALYTNISHMRPWIEKQL 324

Fly 487 486
Fly 325 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	101/239 (42%)
		Tryp_SPc	252..482	CDD:214473	97/234 (41%)
CG18557	NP_608721.1	Tryp_SPc	88..323	CDD:238113	101/239 (42%)
CG18557	NP_608721.1	Tryp_SPc	90..320	CDD:214473	97/234 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471499
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BM7R
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	132	1.000	Inparanoid score	I4490
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D23222at50557
OrthoFinder	1	1.000	-	-		FOG0003848
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.900