DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and CG4259

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster

Alignment Length:	237	Identity:	85/237 - (35%)
Similarity:	119/237 - (50%)	Gaps:	26/237 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 AQYPWAVAIFHNG----QYLAGGSLIQPNVVLTVAHRVI-TIETELVVRAGDWDLKSDREIFLSE 314
            |.:||.|::....    :|:..||||.||||||.||.:. |.:.:||||||:||..:     .::
  Fly    37 ATFPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKYDLVVRAGEWDTST-----TAD 96

  Fly   315 QREVERAVI----HEGFDFKSGANNLALLFLNSPFKLNDHIRTICLPTPNKSFAGRRCTVAGWGK 375
            |:.|:..|:    ||.|:..:..||:|||.|.|.|::..:|..|.|...........|...||||
  Fly    97 QQHVDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQEAGIQKGSCFFNGWGK 161

  Fly   376 MRYEDQRYSTVLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNIICAGGELGRDTCTGDGGSALF 440
            :......|.||||.||:.:::..:|     |:|     :||...||..|..|.| |:||||:.|.
  Fly   162 VYLNSTDYPTVLKTVQVDLLSMGMC-----SSR-----KLPIQQICGKGLEGID-CSGDGGAPLV 215

  Fly   441 CSIGGENSGVYEQAGIVNWGVGCGQEGIPAIYTEVSKFTNWI 482
            |.| ......|.|.|||||......|....::|.|:....||
  Fly   216 CRI-LTYPYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWI 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	85/237 (36%)
		Tryp_SPc	252..482	CDD:214473	83/235 (35%)
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	84/235 (36%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	82/233 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471519
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BM7R
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003848
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.740