DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and Ser6

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_523426.1	Gene:	Ser6 / 33073	FlyBaseID:	FBgn0011834	Length:	259	Species:	Drosophila melanogaster

Alignment Length:	257	Identity:	76/257 - (29%)
Similarity:	119/257 - (46%)	Gaps:	45/257 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 NGLQMVEGITIDQARPAQYPWAVAIFHNGQYLAGGSLIQPNVVLTVAH--------RVIT-IETE 294
            || ::|.|   :.|...|:|..|::.:.|.:..|||::....:||.||        .||| |..|
  Fly    29 NG-RVVGG---EDAVKNQFPHQVSLRNAGSHSCGGSILTRTYILTAAHCVSNEDVNHVITPIAAE 89

  Fly   295 -LVVRAGDWDLKSDREIFLSEQREVERAVIHEGFDFKSGANNLALLFLNSPFKLNDHIRTICLPT 358
             ..:|||..|..|...:.     :|...::||  ::.:..|::|||.|.||..|:..|:.|.|||
  Fly    90 RFTIRAGSNDRFSGGVLV-----QVAEVIVHE--EYGNFLNDVALLRLESPLILSASIQPIDLPT 147

  Fly   359 PNKSFAGRRCTVAGWGKMRYEDQ--RYSTVLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNIIC 421
            .:.. |.....::|||:::::..  ||   |:...|..:.|..||:.:   ..|.:.||     |
  Fly   148 VDTP-ADVDVVISGWGRIKHQGDLPRY---LQYNTLKSITRQQCEELI---DFGFEGEL-----C 200

  Fly   422 AGGELGRDTCTGD-GGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPAIYTEVSKFTNWI 482
            ...::....|.|| ||.|::      |:.:...||.|  ..|||.. .|..|..|..|.:||
  Fly   201 LLHQVDNGACNGDSGGPAVY------NNQLVGVAGFV--VDGCGST-YPDGYARVFYFKDWI 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	72/246 (29%)
		Tryp_SPc	252..482	CDD:214473	70/242 (29%)
Ser6	NP_523426.1	Tryp_SPc	31..253	CDD:214473	72/252 (29%)
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	74/253 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457618
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840