DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SPH93 and CG9673

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001285346.1	Gene:	CG9673 / 32649	FlyBaseID:	FBgn0030775	Length:	261	Species:	Drosophila melanogaster

Alignment Length:	247	Identity:	62/247 - (25%)
Similarity:	109/247 - (44%)	Gaps:	49/247 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 QYPWAVAIFHNGQYLAGGSLIQPNVVLTVAHRVITI------ETELVVRAGDWDLKSDREIFLSE 314
            :|||:.::.:|..::..|::|..|.:||.||.|.::      .:.|.||.|..:..:...|.
  Fly    39 EYPWSASVRYNKAHVCSGAIISTNHILTAAHCVSSVGITPVDASTLAVRLGTINQYAGGSIV--- 100

  Fly   315 QREVERAVIHEGFDFKSGANNLALLFLNSPFKLNDHIRTICLP-------------TPNKSFAGR 366
              .|:..:||..:.  :..:::|:|.|:.....:|.|:.|.||             .||    |.
  Fly   101 --NVKSVIIHPSYG--NFLHDIAILELDETLVFSDRIQDIALPPTTDEETEDVDAELPN----GT 157

  Fly   367 RCTVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNIICAGGELGRDTC 431
            ...|||||::  .|...|...:|.....::|::||     ...|..:|   :::|.....|...|
  Fly   158 PVYVAGWGEL--SDGTASYKQQKANYNTLSRSLCE-----WEAGYGYE---SVVCLSRAEGEGIC 212

  Fly   432 TGDGGSALFCSIGGENSGVYEQAGIVNWGVG-CGQEGIPAIYTEVSKFTNWI 482
            .||.|:|:.     ::..|..  |:.::..| ||.: .|.:.|.||.:..||
  Fly   213 RGDAGAAVI-----DDDKVLR--GLTSFNFGPCGSK-YPDVATRVSYYLTWI 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	62/247 (25%)
		Tryp_SPc	252..482	CDD:214473	60/245 (24%)
CG9673	NP_001285346.1	Tryp_SPc	28..256	CDD:214473	60/245 (24%)
CG9673	NP_001285346.1	Tryp_SPc	29..259	CDD:238113	62/247 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100