DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and CG31827

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_723923.1	Gene:	CG31827 / 318965	FlyBaseID:	FBgn0051827	Length:	294	Species:	Drosophila melanogaster

Alignment Length:	255	Identity:	122/255 - (47%)
Similarity:	171/255 - (67%)	Gaps:	2/255 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 CGMSNANGLQMVEGITIDQARPAQYPWAVAIFHNGQYLAGGSLIQPNVVLTVAHRVITIETE-LV 296
            ||..|.:.:::...:|..||:||::||.:|:.||...:.|||||.|::|||.|||:...:.| :|
  Fly    31 CGYGNPDAVKVQFNVTEGQAKPAEFPWTIAVIHNRSLVGGGSLITPDIVLTAAHRIFNKDVEDIV 95

  Fly   297 VRAGDWDLKSDREIFLSEQREVERAVIHEGFDFKSGANNLALLFLNSPFKLNDHIRTICLPTPNK 361
            |.||:|:..|..|.:..|:..|.:.|||:.|:::.||||||||||:..|.|...|.||||||..:
  Fly    96 VSAGEWEYGSALEKYPFEEAFVLKMVIHKSFNYQRGANNLALLFLDREFPLTYKINTICLPTQKR 160

  Fly   362 SFAGRRCTVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNIICAGGEL 426
            |.:..||.||||||.::.|..|..||||:.|.:|.|::|:..||.||||..:.||:.:||||||.
  Fly   161 SLSSTRCIVAGWGKYQFSDTHYGGVLKKIDLPIVPRHICQDQLRKTRLGQNYTLPRGLICAGGEK 225

  Fly   427 GRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPAIYTEVSKFTNWITEKL 486
            ..|.||||||.||||.: .|:...:||.|||||||||.::.:||.||:|.:|..||.:::
  Fly   226 DNDACTGDGGGALFCPM-TEDPKQFEQIGIVNWGVGCKEKNVPATYTDVFEFKPWIVQQI 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	118/235 (50%)
		Tryp_SPc	252..482	CDD:214473	115/230 (50%)
CG31827	NP_723923.1	Tryp_SPc	50..283	CDD:238113	117/233 (50%)
CG31827	NP_723923.1	Tryp_SPc	50..280	CDD:214473	115/230 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471510
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BM7R
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	132	1.000	Inparanoid score	I4490
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003848
OrthoInspector	1	1.000	-	-		mtm8716
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890