DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and CG32523

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster

Alignment Length:	253	Identity:	73/253 - (28%)
Similarity:	113/253 - (44%)	Gaps:	38/253 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 QMVEGITIDQARPAQYPWAVAIFHNGQYLAGGSLIQPNVVLTVAHRVITIETELVVRAGDWDLKS 306
            ::|.||   :|:..|:|..:::...|::..||.:|....|:|..|.|  .....||.|..|.:::
  Fly    36 RIVGGI---KAKQGQFPHQISLRLRGEHYCGGVIISATHVITAGHCV--KHGNDVVPADLWSIQA 95

  Fly   307 DREIFLSE--QREVERAVIHEGFDFKSGANNLALLFLNSPFKLNDHIRTICLPT---PNKSFAGR 366
            ...:..|:  :..|...::|..: ...|.|:||:|.|.||...:.:|..|.|.|   ||
  Fly    96 GSLLLSSDGVRIPVAEVIMHPNY-ATGGHNDLAVLRLQSPLTFDANIAAIQLATEDPPN------ 153

  Fly   367 RCT---VAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNIICAGGELGR 428
             |.   ::|||.:. |....|..|..||:..::|..|.....|       .||:.:||.......
  Fly   154 -CVAVDISGWGNIA-EKGPLSDSLLFVQVTSISRGACRWMFYS-------RLPETMICLLHSKNS 209

  Fly   429 DTCTGD-GGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPAIYTEVSKFTNWITEK 485
            ..|.|| ||.|.:   ||:..|:   |.:: .|.|||: ..|..|..:||...||.||
  Fly   210 GACYGDSGGPATY---GGKVVGL---ASLL-LGGGCGR-AAPDGYLRISKVRAWIAEK 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	68/243 (28%)
		Tryp_SPc	252..482	CDD:214473	66/238 (28%)
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	69/248 (28%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	55/202 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457619
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840