DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and Tpsg1

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_783183.1	Gene:	Tpsg1 / 302990	RGDID:	631355	Length:	311	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	77/280 - (27%)
Similarity:	131/280 - (46%)	Gaps:	50/280 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 LLSPSCGMSNAN--GLQMVEGITIDQARPAQYPWAVAIFHNGQYLAGGSLIQPNVVLTVAHRVIT 290
            |..|.||....:  |.::|.|   ..|:...:||..::.....::.||||:.|..|||.||
  Rat    13 LAVPGCGQPQVSHAGSRIVGG---HAAQAGAWPWQASLRLQKVHVCGGSLLSPEWVLTAAH---- 70

  Fly   291 IETELVVRAGDWDLKSDREIFLSEQ--------REVERAVIHEGFDFKSGAN-NLALLFLNSPFK 346
                  ..:|..: .||.|:.|.|.        ..|::.:::.......|:: ::||:.|.:|..
  Rat    71 ------CFSGSVN-SSDYEVHLGELTITLSPHFSTVKQIIMYSSAPGPPGSSGDIALVQLATPVA 128

  Fly   347 LNDHIRTICLPTPNKSF-AGRRCTVAGWG--------KMRYEDQRYSTVLKKVQLLVVNRNVCEK 402
            |:..::.:|||..:..| .|.:|.|.|||        |..|.       |::.::.||:...|.:
  Rat   129 LSSQVQPVCLPEASADFHPGMQCWVTGWGYTQEGEPLKPPYN-------LQEAKVSVVDVETCSQ 186

  Fly   403 FLRSTRLGAKFELPKNIICAGGELGRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEG 467
            ...|:. |:..:  .:::||.|.  .|.|..|.|..|.|.:    :|:::|||:|:||.|||:..
  Rat   187 AYSSSN-GSLIQ--SDMLCAWGP--GDACQDDSGGPLVCRV----AGIWQQAGVVSWGEGCGRPD 242

  Fly   468 IPAIYTEVSKFTNWITEKLL 487
            .|.:|..|:.:.|||...:|
  Rat   243 RPGVYARVTAYVNWIHRHIL 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	69/252 (27%)
		Tryp_SPc	252..482	CDD:214473	67/247 (27%)
Tpsg1	NP_783183.1	Tryp_SPc	29..257	CDD:214473	69/257 (27%)
Tpsg1	NP_783183.1	Tryp_SPc	30..260	CDD:238113	71/259 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346359
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840