DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and Prss30

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_955403.2	Gene:	Prss30 / 287106	RGDID:	735142	Length:	304	Species:	Rattus norvegicus

Alignment Length:	283	Identity:	80/283 - (28%)
Similarity:	131/283 - (46%)	Gaps:	51/283 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 GSSELLSPSCGMSNANGLQMVEGITIDQARPAQYPWAVAIFHNGQ-YLAGGSLIQPNVVLTVAH- 286
            |..::|....|       ::|.|   ..|...::||.|::....: ::.|||||....|||.||
  Rat    19 GRGDILHSGAG-------KIVGG---QDAPEGRWPWQVSLRTEKEGHICGGSLIHEVWVLTAAHC 73

  Fly   287 --RVITIETELVVRAGDWDLKSDREIFLSEQRE----VERAVIHEGF---DFKSGANNLALLFLN 342
              |.:. .:...|:.|...|.      |:|...    |....::..:   |..||  ::|||.|:
  Rat    74 FCRPLN-SSFYHVKVGGLTLS------LTEPHSTLVAVRNIFVYPTYLWEDASSG--DIALLRLD 129

  Fly   343 SPFKLNDHIRTICLP------TPNKSFAGRRCTVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCE 401
            :|.: ......:|||      ||     |..|.|.|||..  .::..::||:::.:.:::...||
  Rat   130 TPLQ-PSQFSPVCLPQAQAPLTP-----GTVCWVTGWGAT--HERELASVLQELAVPLLDSEDCE 186

  Fly   402 KF--LRSTRLGAKFELPKNIICAGGELG-RDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGC 463
            :.  :..|.|..|..:..:::|||...| :|:|.||.|..|.|:|   ||. :.|.||.:||:||
  Rat   187 RMYHIGETSLSGKRVIQSDMLCAGFVEGQKDSCQGDSGGPLVCAI---NSS-WIQVGITSWGIGC 247

  Fly   464 GQEGIPAIYTEVSKFTNWITEKL 486
            .:...|.:||.|..:.:||...|
  Rat   248 ARPNKPGVYTRVPDYVDWIQRTL 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	74/254 (29%)
		Tryp_SPc	252..482	CDD:214473	72/249 (29%)
Prss30	NP_955403.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910