DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and CG30289

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_726081.1	Gene:	CG30289 / 246532	FlyBaseID:	FBgn0050289	Length:	316	Species:	Drosophila melanogaster

Alignment Length:	274	Identity:	74/274 - (27%)
Similarity:	125/274 - (45%)	Gaps:	28/274 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 SELLSPSCGMSNANGL--QMVEGITIDQARPAQYPWAVAIFHNGQYLAGGSLIQPNVVLTVAHRV 288
            |.||..:||:|..:..  .:..|.   :....:.||.|.::.:..  .|||||....|||.|| .
  Fly    23 SRLLVENCGISKDDPYVPNIFGGA---KTNIQENPWMVLVWSSKP--CGGSLIARQFVLTAAH-C 81

  Fly   289 ITIETELVVRAGDWDLKSDREIFLSE-------QREVERAVIHEGFDFKSGANNLALLFLNSPFK 346
            ::.| :|.||.||::........|:.       ...|:..::||.::..:..|::|||.::...:
  Fly    82 VSFE-DLYVRLGDYETLDPMPYCLNNHCIPKFYNISVDMKIVHENYNGITLQNDIALLRMSEAVE 145

  Fly   347 LNDHIRTICLPTPNKSFAGRRCTVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCE-KFLRSTRLG 410
            .:|::|.|||....:..:....||.|||:..|  .::|.:|....|..::.:.|. ||.:
  Fly   146 YSDYVRPICLLVGEQMQSIPMFTVTGWGETEY--GQFSRILLNATLYNMDISYCNIKFNK----- 203

  Fly   411 AKFELPKNIICAGGELGRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPAIYTEV 475
               :..::.||||.... :||.||.|..|.......|..:..|.|:|::|.......:..:||.|
  Fly   204 ---QADRSQICAGSHTS-NTCKGDSGGPLSSKFHYGNRLLSFQYGLVSYGSERCAANVAGVYTNV 264

  Fly   476 SKFTNWITEKLLPF 489
            |....||..|::.|
  Fly   265 SYHREWIFNKMVQF 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	65/242 (27%)
		Tryp_SPc	252..482	CDD:214473	63/237 (27%)
CG30289	NP_726081.1	Tryp_SPc	42..271	CDD:214473	64/246 (26%)
CG30289	NP_726081.1	Tryp_SPc	42..271	CDD:238113	64/246 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010