DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and CG30088

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_725488.3	Gene:	CG30088 / 246447	FlyBaseID:	FBgn0050088	Length:	281	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	74/275 - (26%)
Similarity:	124/275 - (45%)	Gaps:	44/275 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 SSELLSPSCGMSNANGL--QMVEGITIDQARPAQYPWAVAIFHNGQYLAGGSLIQPNVVLTVAHR 287
            ::..|.||||:|..:.:  ::|.|   .:|.....|:...::::.:...||::|....:||.||
  Fly    25 AANFLIPSCGVSYESNVATRIVRG---KEAMLKSAPFMAYLYYSSEIHCGGTIISSRYILTAAH- 85

  Fly   288 VITIETELVVRAGDWDLKSDREIF------LSEQREVERAVIHEGFDFKSGANNLALLFLNSPFK 346
              .:...|.||.|:.|:..:.:..      .:|:.::..|..::.|| :..||::|||.|:...:
  Fly    86 --CMRPYLKVRLGEHDITRNPDCQGGSCSPPAEEFDIVLATKYKRFD-RFLANDIALLKLSRNIR 147

  Fly   347 LNDHIRTICL-----PTPN----KSFAGRRCTVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCEK 402
            .|.||:.|||     ..||    ::|        |||:.  |....:.||:...|...:...|..
  Fly   148 FNVHIQPICLILNPAAAPNVHEFQAF--------GWGQT--ETNHSANVLQTTVLTRYDNRHCRS 202

  Fly   403 FLRSTRLGAKFELPKNIICAGGELGRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEG 467
            .|       ...:..|.:|.|.: |.|||:||.|..|...:..:....|.|.|||::|....|.
  Fly   203 VL-------SMPITINQLCVGFQ-GSDTCSGDSGGPLVTKVNYDGVWRYLQLGIVSFGDDKCQS- 258

  Fly   468 IPAIYTEVSKFTNWI 482
             |.:||.|..:..||
  Fly   259 -PGVYTYVPNYIRWI 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	66/248 (27%)
		Tryp_SPc	252..482	CDD:214473	64/244 (26%)
CG30088	NP_725488.3	Tryp_SPc	44..272	CDD:214473	66/254 (26%)
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	68/255 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010