DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and Prss29

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_444490.2	Gene:	Prss29 / 114662	MGIID:	2149952	Length:	279	Species:	Mus musculus

Alignment Length:	289	Identity:	82/289 - (28%)
Similarity:	137/289 - (47%)	Gaps:	44/289 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 VGSSELLSPSCGMSNANGLQMVEGITIDQARP-AQYPWAVAI----------FHNGQYLAGGSLI 276
            :|.|...:|:.|   ..|:.|  ||....:.| .::||.|::          .||    .|||:|
Mouse    12 LGCSIAGTPAPG---PEGVLM--GIVGGHSAPQGKWPWQVSLRIYRYYWAFWVHN----CGGSII 67

  Fly   277 QPNVVLTVAHRVITIETE---LVVRAGDWDLKSDREIFLSEQREVERAVIHEGFDFKSGANNLAL 338
            .|..|||.||.:...:.:   ..:|.|:..|...:|:.     .|.|.:||..|......:::||
Mouse    68 HPQWVLTAAHCIRERDADPSVFRIRVGEAYLYGGKELL-----SVSRVIIHPDFVHAGLGSDVAL 127

  Fly   339 LFLNSPFKLNDHIRTICLPTPNKSFAGRR-CTVAGWGKM---RYEDQRYSTVLKKVQLLVVNRNV 399
            |.|....:...:::.:.||:.:.....:. |.|.|||.:   |.....|.  |::||:.:::.::
Mouse   128 LQLAVSVQSFPNVKPVKLPSESLEVTKKDVCWVTGWGAVSTHRSLPPPYR--LQQVQVKIIDNSL 190

  Fly   400 CEKF----LRSTRLGAKFELPKNIICAGGELGRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWG 460
            ||:.    .|....|.|..| |:::|||.: |:|:|.||.|..|.|::    :|.:...|:|:||
Mouse   191 CEEMYHNATRHRNRGQKLIL-KDMLCAGNQ-GQDSCYGDSGGPLVCNV----TGSWTLVGVVSWG 249

  Fly   461 VGCGQEGIPAIYTEVSKFTNWITEKLLPF 489
            .||.....|.:|..|..|..|||:::..|
Mouse   250 YGCALRDFPGVYARVQSFLPWITQQMQRF 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	73/256 (29%)
		Tryp_SPc	252..482	CDD:214473	70/251 (28%)
Prss29	NP_444490.2	Tryp_SPc	31..274	CDD:238113	74/259 (29%)
Prss29	NP_444490.2	Tryp_SPc	31..271	CDD:214473	71/256 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842927
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840