Protein Alignment SPH93 and MASP2

DIOPT Version :9

• Sequence 1: NP_609840.1
• Gene: SPH93 / 35049
• FlyBaseID: FBgn0032638
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_006601.2
• Gene: MASP2 / 10747
• HGNCID: 6902
• Length: 686
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 122/484 - (25%)
• Similarity: 175/484 - (36%)
• Gaps: 140/484 - (28%)

  Fly    85 PTRELTRDRPNTIESQVKEINDFSGRPTNNERN------PATEPNNGGYTTP------------- 130
            |.|..|:....||.....|..|.:|...:....      |...||  |:.:|
Human   264 PHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPCPYPMAPPN--GHVSPVQAKYILKDSFSI 326

  Fly   131 --NGGYPVNNGGYPV--------NNGGY------------------PSNNGGYPSNNG------- 160
              ..||.:..|..|:        .:|.:                  ||....|.:..|
Human   327 FCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAV 391

  Fly   161 -GYPVNNGGYPVNNGGYPANNGGYPANNGGYPTTNVGNPTNNGGNPTTNFGNPTNNGGNPTTNVG 224
             .|......|.:.     .|:|.|.....|:.|::.|..
Human   392 IQYSCEETFYTMK-----VNDGKYVCEADGFWTSSKGEK-------------------------- 425

  Fly   225 SSELLSPSCGMS-NANGLQMVEGITIDQARPAQYPWAVAIFHNGQYLAGGSLIQPNVVLTVAHRV 288
            |..:..|.||:| ...|.::..|   .:|:|..:||.|.|.  |...|.|:|:..|.|||.||.|
Human   426 SLPVCEPVCGLSARTTGGRIYGG---QKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAV 485

  Fly   289 ITIE---TELVVRAGDWDLKSDREIFLSEQREVERAVIHEGFDFKSG-ANNLALLFLNSPFKLND 349
            ...:   :.|.:|.|.....|..    ..|...|...||||:...:| .|::||:.||:...:|.
Human   486 YEQKHDASALDIRMGTLKRLSPH----YTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINS 546

  Fly   350 HIRTICLPTPN-KSF-----AGRRCTVAGWGKMRYEDQR--YSTVLKKVQLLVVNRNVCEKFLRS 406
            :|..||||... :||     .|   |.:|||.    .||  .:..|..|.:.:|:...|.
Human   547 NITPICLPRKEAESFMRTDDIG---TASGWGL----TQRGFLARNLMYVDIPIVDHQKCT----- 599

  Fly   407 TRLGAKFELP--------KNIICAGGEL-GRDTCTGDGGSAL-FCSIGGENSGVYEQAGIVNWG- 460
                |.:|.|        .|::|||.|. |:|:|.||.|.|| |.....|...|   .|||:||
Human   600 ----AAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFV---GGIVSWGS 657

  Fly   461 VGCGQEGIPAIYTEVSKFTNWITEKLLPF 489
            :.||:.|...:||:|..:..||...:..|
Human   658 MNCGEAGQYGVYTKVINYIPWIENIISDF 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089	12/86 (14%)
		Tryp_SPc	250..485	CDD:238113	84/257 (33%)
		Tryp_SPc	252..482	CDD:214473	82/252 (33%)
MASP2	NP_006601.2	CUB	28..134	CDD:214483
		EGF_CA	138..176	CDD:214542
		CUB	184..293	CDD:278839	8/28 (29%)
		CCP	300..361	CDD:214478	10/62 (16%)
		Sushi	366..430	CDD:278512	13/94 (14%)
		Tryp_SPc	444..679	CDD:214473	83/262 (32%)
		Tryp_SPc	445..682	CDD:238113	85/264 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910