DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and zgc:163079

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001077051.2	Gene:	zgc:163079 / 100006550	ZFINID:	ZDB-GENE-030131-7428	Length:	313	Species:	Danio rerio

Alignment Length:	280	Identity:	81/280 - (28%)
Similarity:	126/280 - (45%)	Gaps:	39/280 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 VGSSELLSPSCGMSNANGLQMVEGITIDQARPAQYPWAVAIFHNG--QYLAGGSLIQPNVVLTVA 285
            :|.|::    ||.:..| .:::.|:...|   ..:||..:|....  ::..|||||....|||.|
Zfish    21 LGQSDV----CGRAPLN-TKIIGGLNATQ---GSWPWQASINLKATEEFYCGGSLINKGWVLTTA 77

  Fly   286 HRVITI--ETELVVRAGDWDLKSDREIFLSEQREVERAVIHEGFDFKSGANNLALLFLNSPFKLN 348
             :|..:  .:::||..|...........:|  |.|.:.:.|.  ::.|..:|||||.|:||...:
Zfish    78 -KVFALMPASDIVVYLGRQTQNGSNPYEIS--RTVTKIIKHP--NYNSLDSNLALLKLSSPVTFS 137

  Fly   349 DHIRTICLPTPNKSFA-GRRCTVAGWGKMR----YEDQRYSTVLKKVQLLVVNRNVCEKFLRSTR 408
            |:|:.:||......|. |....|.|||.:.    .|:.....||::|:..:||...|.......
Zfish   138 DYIKPVCLAAAGSVFVDGTASWVTGWGYLNRPATVEEIMLPDVLQEVEAPIVNNFECNAAYGGI- 201

  Fly   409 LGAKFELPKNIICAG--GELGRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPAI 471
                  :...::|||  .|.|:..|.||.|..|....|    .::.|:|:|..|. ||..|.|.|
Zfish   202 ------ITNKLLCAGYLNEDGKAPCAGDVGGPLVIKQG----AIWIQSGVVVSGY-CGLPGYPTI 255

  Fly   472 YTEVSKFTNWI---TEKLLP 488
            |..||::.:||   |...||
Zfish   256 YVRVSEYEDWISYYTNSSLP 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	73/248 (29%)
		Tryp_SPc	252..482	CDD:214473	69/240 (29%)
zgc:163079	NP_001077051.2	Tryp_SPc	35..266	CDD:214473	71/250 (28%)
zgc:163079	NP_001077051.2	Tryp_SPc	36..267	CDD:238113	72/250 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587518
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930