DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and LOC100004427

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_005163955.1	Gene:	LOC100004427 / 100004427	-ID:	-	Length:	302	Species:	Danio rerio

Alignment Length:	286	Identity:	87/286 - (30%)
Similarity:	118/286 - (41%)	Gaps:	62/286 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 VGSSELLSPSCGMSNAN-----GLQMVEGITIDQARPAQYPWAVAI-FHN-GQYLAGGSLIQPNV 280
            :|.|::    ||.:..|     ||...||         .:||..:| |.: ||:...||||....
Zfish    21 LGQSDV----CGRAPLNTKIVGGLNATEG---------SWPWQASINFKSTGQFFCSGSLISERW 72

  Fly   281 VLTVAHRVITIETELVVRAGDWDLKSDREIFL-------SEQREVERAVIHEGFDFKSGANNLAL 338
            |||.|.....|..            ||..|:|       |...|:.|.||.     .|...::||
Zfish    73 VLTAASCFQRINV------------SDVVIYLGRLTTNGSNPYEIPRTVIQ-----VSVTEDIAL 120

  Fly   339 LFLNSPFKLNDHIRTICLPTPNKSFA-GRRCTVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCEK 402
            :.|:|.....|:||.:||......|. |....|.|||.....:...|.:||:|:..:||...|..
Zfish   121 VQLSSSVTFTDYIRPVCLAAAGSVFVDGTESWVTGWGSTSSTNVILSDMLKEVEAPIVNNIECSN 185

  Fly   403 FLRSTRLGAKFELPKNIICAG--GELGRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQ 465
            ....|.|       .|:||||  .|.|:..|..|.||.|....|.:    :.|:|:|.: ..|||
Zfish   186 INGITNL-------DNVICAGFVNETGKAPCWEDFGSPLVTRQGSQ----WIQSGVVVF-TFCGQ 238

  Fly   466 EGIPAIYTEVSKFTNWI---TEKLLP 488
            .|.|.:|..||::..||   |...||
Zfish   239 NGFPTLYARVSEYEEWIRNYTSSSLP 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	76/249 (31%)
		Tryp_SPc	252..482	CDD:214473	73/241 (30%)
LOC100004427	XP_005163955.1	Tryp_SPc	35..255	CDD:214473	77/257 (30%)
LOC100004427	XP_005163955.1	Tryp_SPc	36..257	CDD:238113	79/258 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587519
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930