DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SPH93 and si:dkey-16l2.17

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_001341498.1	Gene:	si:dkey-16l2.17 / 100001520	ZFINID:	ZDB-GENE-141212-262	Length:	305	Species:	Danio rerio

Alignment Length:	277	Identity:	90/277 - (32%)
Similarity:	142/277 - (51%)	Gaps:	33/277 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 GSSELLSPSCGMSNANGLQMVEGITIDQARPAQYPWAVAI--FHNGQYLAGGSLIQPNVVLTVAH 286
            |.|..|:..||.... |.::|.|:   :|.|..:||.|.|  ..|| ::.|||:|..|.||:.||
Zfish    14 GLSTCLAQVCGRPPL-GKRIVGGV---EASPGSWPWQVDIQMGSNG-HVCGGSIIAKNWVLSAAH 73

  Fly   287 RVITIETELVVRAGDWDLKSDREIF-----LSEQREVERAVIHEGFDFKSGANNLALLFLNSPFK 346
               .......|.|  :.|...|.:.     ..:...|:|.||.||:....|..::||:.|.:|..
Zfish    74 ---CFPNPSEVSA--YTLYMGRHLLNGYNQFEKVSYVQRVVIPEGYTDPQGGRDVALVQLRAPVS 133

  Fly   347 LNDHIRTICLPTPNKSF-AGRRCTVAGWG-KMRYEDQRYSTVLKKVQLLVVNRNVCE---KFLRS 406
            ..|.|:.:|||..:..| :|..|.|.||| |........:..|::|::.:::::.|:   :.|.|
Zfish   134 WTDRIQPVCLPFADFQFNSGTLCYVTGWGHKQEGVSLTGAAALREVEVPIIDQSSCQFMYQILSS 198

  Fly   407 TRLGAKFELPKNIICAG-GELGRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPA 470
            .  .:..::..::|||| .|.|:|:|.||.|..|.|.:|   :|.:.|||:|::|:||.|:..|.
Zfish   199 D--SSTVDILSDMICAGYKEGGKDSCQGDSGGPLVCPVG---NGTWIQAGVVSFGLGCAQKNRPG 258

  Fly   471 IYTEVSKFTNWITEKLL 487
            ||:.||.|     |||:
Zfish   259 IYSRVSSF-----EKLI 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	79/247 (32%)
		Tryp_SPc	252..482	CDD:214473	79/242 (33%)
si:dkey-16l2.17	XP_001341498.1	Tryp_SPc	32..273	CDD:238113	84/258 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587574
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840