Protein Alignment dl and rel

DIOPT Version :10

• Sequence 1: NP_724054.1
• Gene: dl / 35047
• FlyBaseID: FBgn0260632
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: NP_001001841.2
• Gene: rel / 415101
• ZFINID: ZDB-GENE-040718-255
• Length: 596
• Species: Danio rerio
• Alignment Length: 559
• Identity: 182/559 - (32%)
• Similarity: 250/559 - (44%)
• Gaps: 131/559 - (23%)

  Fly    46 KPYVKITEQPAGKALRFRYECEGRSAGSIPGVNSTPENKTYPTIEIVGYKGRAVVVVSCVTKDTP 110
            :|.|:|.|||..:.:||||:|||||||||||..|:..|:|||:|:|:...|:..|.|:.|||..|
Zfish    17 EPCVQIFEQPKQRGMRFRYKCEGRSAGSIPGERSSDNNRTYPSIQILNVTGKGKVRVTLVTKSEP 81

  Fly   111 YRPHPHNLVGKEGCKKGVCTLEINSETMRAVFSNLGIQCVKKKDIEAALKAREEIRVDPFKTGFS 175
            |:||||:||||: ||.|....|...|.....|.|||||||::::::.|:..|....::||.....
Zfish    82 YKPHPHDLVGKD-CKDGYYEAEFGPERRAIAFQNLGIQCVRRREVKDAIMQRVTRGINPFNVPRE 145

  Fly   176 HRFQPSSIDLNSVRLCFQVFMESEQKGRFTSPLPPVVSEPIFDKKA--MSDLVICRLCSCSATVF 238
            ...|....|||.||||||::::.| .|.:::.|||:||.||:|.:|  .::|.|||:...|.:|.
Zfish   146 QLLQTEEYDLNVVRLCFQIYLQDE-SGMYSTMLPPIVSNPIYDNRAPNTAELRICRVNKNSGSVK 209

  Fly   239 GNTQIILLCEKVAKEDISVRFFEEKNGQSVWEAFGDFQHTDVHKQTAITFKTPRYHTLDITEPAK 303
            |..:|.|||:||.|:||.||||.:     .|||.|.|...|||:|.||.||||.|....||.|..
Zfish   210 GGDEIFLLCDKVQKDDIEVRFFTQ-----TWEAKGSFSQADVHRQVAIVFKTPAYCDTSITAPVT 269

  Fly   304 VFIQLRRPSDGVTSEALPFEYVPMDSGKHTFWNLHRHLKRKPD---------------------- 346
            |.:|||||:|...||.:.|.|:|.|...:..    |..|||.|
Zfish   270 VRMQLRRPTDQEVSEPMEFRYLPDDKDPYGC----REKKRKIDMQMKSSFPSFSQEAMSFMNRTK 330

  Fly   347 ----EDLFQQILRLDAKREVQPP--------------------------------------TIEV 369
                .:|..|.::.:.....:||                                      |.:|
Zfish   331 AVSSTNLMNQRIKTEPPNFYRPPNQGVARQNQPVYYNKGLRSCPMMPHPSETTTQGALSQWTSQV 395

  Fly   370 IDLDTPK--IDVQREIPSEMEFNHEESQQSEPALEQ---------------------EQSVQQEQ 411
            .:...|.  :.:|:..||....:..|:..|.|.|..                     .|.|||.|
Zfish   396 TNTSVPNNVVSLQQVNPSPNMPSAGENGNSLPLLTSMDLEILQPNGPTGNQPRQDLLNQQVQQSQ 460

  Fly   412 YTQEQ----------SLQQEQYTQE---------------QSLQQEQYLQQL--EQQQSFQL-EE 448
            ...::          |.||.|.||.               .|..::..||.|  ..|...|| :|
Zfish   461 QPPQRQGQEGAWYNYSSQQPQNTQNGASGASGSLATGYQFTSGLEDDILQSLMGNHQPGIQLKQE 525

  Fly   449 PMQQDQELPAQQSFD--QAIDHLPDHTSDHIPEDMEAAD 485
            |.......|...| |  |:...|.:..:...||.|...|
Zfish   526 PQGLSNMAPLVNS-DCVQSFTALLNCNNGSTPEHMRQID 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dl	NP_724054.1	RHD-n_Dorsal_Dif	47..220	CDD:143647	81/172 (47%)
		IPT_NFkappaB	225..326	CDD:238582	50/100 (50%)
rel	NP_001001841.2	RHD-n_c-Rel	18..189	CDD:143649	81/172 (47%)
		IPT_NFkappaB	196..292	CDD:238582	50/100 (50%)