Protein Alignment dl and Rela

DIOPT Version :9

• Sequence 1: NP_001286014.1
• Gene: dl / 35047
• FlyBaseID: FBgn0260632
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: XP_006531757.1
• Gene: Rela / 19697
• MGIID: 103290
• Length: 556
• Species: Mus musculus
• Alignment Length: 601
• Identity: 190/601 - (31%)
• Similarity: 273/601 - (45%)
• Gaps: 144/601 - (23%)

  Fly    47 PYVKITEQPAGKALRFRYECEGRSAGSIPGVNSTPENKTYPTIEIVGYKGRAVVVVSCVTKDTPY 111
            |||:|.|||..:.:||||:|||||||||||..||...||:|||:|.||.|...|.:|.||||.|:
Mouse    26 PYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPH 90

  Fly   112 RPHPHNLVGKEGCKKGVCTLEINSETMRAVFSNLGIQCVKKKDIEAALKAREEIRVDPFKTGFSH 176
            |||||.||||: |:.|....::..:.....|.|||||||||:|:|.|:..|.:...:||......
Mouse    91 RPHPHELVGKD-CRDGYYEADLCPDRSIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFHVPIEE 154

  Fly   177 RFQPSSIDLNSVRLCFQVFMESEQKGRFTSP--LPPVVSEPIFDKKA--MSDLVICRLCSCSATV 237
              |....|||:|||||||.:. :..||   |  |.||:|.||||.:|  .::|.|||:...|.:.
Mouse   155 --QRGDYDLNAVRLCFQVTVR-DPAGR---PLLLTPVLSHPIFDNRAPNTAELKICRVNRNSGSC 213

  Fly   238 FGNTQIILLCEKVAKEDISVRFFEEKNGQSVWEAFGDFQHTDVHKQTAITFKTPRYHTLDITEPA 302
            .|..:|.|||:||.||||.|.|    .|.. |||.|.|...|||:|.||.|:||.|....:..|.
Mouse   214 LGGDEIFLLCDKVQKEDIEVYF----TGPG-WEARGSFSQADVHRQVAIVFRTPPYADPSLQAPV 273

  Fly   303 KVFIQLRRPSDGVTSEALPFEYVPMDSGKHTFWNLHRHLKRKPDEDLFQQILR---LDAKREVQP 364
            :|.:|||||||...||.:.|:|:|....:|..     ..|||...:.|:.|::   .:...|.:|
Mouse   274 RVSMQLRRPSDRELSEPMEFQYLPDTDDRHRI-----EEKRKRTYETFKSIMKKSPFNGPTEPRP 333

  Fly   365 PTIEVIDLDTPKIDVQREIPSEMEFNHEESQQSEPALEQEQSVQQEQYTQEQSLQQEQYTQEQSL 429
            ||..:            .:|:     ...:...:||        .:.||...||        .::
Mouse   334 PTRRI------------AVPT-----RNSTSVPKPA--------PQPYTFPASL--------STI 365

  Fly   430 QQEQYLQQLEQQQSFQLEEPMQQDQELPAQQSFDQAIDHLPDHT--------------------- 473
            ..:::...|                 ||:.|..:||:...|...
Mouse   366 NFDEFSPML-----------------LPSGQISNQALALAPSSAPVLAQTMVPSSAMVPLAQPPA 413

  Fly   474 -------------SDHIPEDMEAADAH-AEAEAHRLRSEQEKEIDTIIDEKV------------- 511
                         |..:|:..:|.:.. :||..| |:.:.::::..::....
Mouse   414 PAPVLTPGPPQSLSAPVPKSTQAGEGTLSEALLH-LQFDADEDLGALLGNSTDPGVFTDLASVDN 477

  Fly   512 RELEQLDLGQQL-------EPRPLTANDKITEWMKSSEIEQQVHEPSPTAEADVLDSALEISKAD 569
            .|.:|| |.|.:       ||..:...:.||..:..|   |:..:|:||        .|..|...
Mouse   478 SEFQQL-LNQGVSMSHSTAEPMLMEYPEAITRLVTGS---QRPPDPAPT--------PLGTSGLP 530

  Fly   570 KTL--DELLETVAELD 583
            ..|  ||...::|::|
Mouse   531 NGLSGDEDFSSIADMD 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dl	NP_001286014.1	RHD-n_Dorsal_Dif	47..220	CDD:143647	89/174 (51%)
		IPT_NFkappaB	225..326	CDD:238582	47/100 (47%)
Rela	XP_006531757.1	RHD-n_RelA	26..194	CDD:143645	89/174 (51%)
		IPT_NFkappaB	201..297	CDD:238582	47/100 (47%)
		PHA03247	<262..528	CDD:223021	62/333 (19%)
		DUF5364	<451..539	CDD:375130	19/99 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847944
Domainoid	1	1.000	166	1.000	Domainoid score	I3870
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391433at33208
OrthoFinder	1	1.000	-	-		FOG0002243
OrthoInspector	1	1.000	-	-		mtm8810
orthoMCL	1	0.900	-	-		OOG6_105422
Panther	1	1.100	-	-	LDO	PTHR24169
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4542
SonicParanoid	1	1.000	-	-		X2257
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.840