Protein Alignment CG15141 and UBR7

DIOPT Version :10

• Sequence 1: NP_609837.1
• Gene: CG15141 / 35044
• FlyBaseID: FBgn0032635
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_786924.2
• Gene: UBR7 / 55148
• HGNCID: 20344
• Length: 425
• Species: Homo sapiens
• Alignment Length: 427
• Identity: 164/427 - (38%)
• Similarity: 231/427 - (54%)
• Gaps: 61/427 - (14%)

  Fly    21 QSTITMLDVLEQEKELEDEYAAVLGASDEKSCTYAKGPIGRQALYSCLTCCPEAREDLDKAAGVC 85
            :..::::||||:::|||:|..||||.||.:.|:|::|.:.|||||:|.||.||..|    .||:|
Human    15 EPVVSLVDVLEEDEELENEACAVLGGSDSEKCSYSQGSVKRQALYACSTCTPEGEE----PAGIC 75

  Fly    86 LACSYRCHEHHELVELYTKRNFRCDCPTQRLG--KCSLNPQVEGVQPRNVGNLYNQNFQGLYCKC 148
            |||||.||..|:|.||||||||||||...:..  :|.|.|....|   |.||.||.||.||||.|
Human    76 LACSYECHGSHKLFELYTKRNFRCDCGNSKFKNLECKLLPDKAKV---NSGNKYNDNFFGLYCIC 137

  Fly   149 KRPYPDPDRTVEEVMLQCAICEDWFHLPHMKA--PGASDKWLDVCSEMICDGCMDAKPFLKDYT- 210
            |||||||:..:.:.|:||.:||||||..|:.|  |.:.|     ..||:|..||....||..|.
Human   138 KRPYPDPEDEIPDEMIQCVVCEDWFHGRHLGAIPPESGD-----FQEMVCQACMKRCSFLWAYAA 197

  Fly   211 -------------------GLALQPVL-------EDA--KEDKPEA---DDSQLKNELDRSIC-- 242
                               |:..|.|:       :|:  |||.||.   |..::|.|.:...|
Human   198 QLAVTKISTEDDGLVRNIDGIGDQEVIKPENGEHQDSTLKEDVPEQGKDDVREVKVEQNSEPCAG 262

  Fly   243 -----DIMKVPEGESQPDEGEPSQKRAKLDDCRRPKPTKEHQGAAFWTNDWRKSLCQCSECLSLY 302
                 |:..|.:.||...|   |:...||.:.:..:..|: ..|.:|..:||..||.|.:|:.:|
Human   263 SSSESDLQTVFKNESLNAE---SKSGCKLQELKAKQLIKK-DTATYWPLNWRSKLCTCQDCMKMY 323

  Fly   303 KELAVEFLLDVEDSAKTYEERGMKRAEENSSYEQGIRALASIDRTQQIDAITEYNRMKDKLKEYL 367
            .:|.|.||.|..|:...||.:| |.|:.....:..:..|:|::|.||::.|.|||.:|.:||:||
Human   324 GDLDVLFLTDEYDTVLAYENKG-KIAQATDRSDPLMDTLSSMNRVQQVELICEYNDLKTELKDYL 387

  Fly   368 QAFAASKKVVTEEDINRFFAGMRNENNANL-GQPYFC 403
            :.||....||..|||.:||...:::....: |..|:|
Human   388 KRFADEGTVVKREDIQQFFEEFQSKKRRRVDGMQYYC 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15141	NP_609837.1	UBR-box_UBR7	52..123	CDD:439075	40/72 (56%)
		PHD_UBR7	145..199	CDD:277017	26/55 (47%)
UBR7	NP_786924.2	UBR-box_UBR7	45..115	CDD:439075	40/73 (55%)
		PHD_UBR7	134..185	CDD:277017	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	225..246		6/20 (30%)