DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15141 and Ubr7

DIOPT Version :9

Sequence 1:	NP_609837.1	Gene:	CG15141 / 35044	FlyBaseID:	FBgn0032635	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	XP_006240537.1	Gene:	Ubr7 / 314399	RGDID:	1359144	Length:	445	Species:	Rattus norvegicus

Alignment Length:	448	Identity:	160/448 - (35%)
Similarity:	223/448 - (49%)	Gaps:	83/448 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 QSTITMLDVLEQEKELEDEYAAVLGASDEKSCTYAKGPIGRQALYSCLTCCPEAREDLDKAAGVC 85
            :..::::||||:::|||:|..||||.||.:.|:|::|.:.|||||:|.||.||..|    .||:|
  Rat    15 EPVVSLVDVLEEDEELENEACAVLGGSDSEKCSYSQGSVKRQALYACSTCTPEGEE----PAGIC 75

  Fly    86 LACSYRCHEHHELVELYTKRNFRCDCPTQRLG--KCSLNPQVEGVQPRNVGNLYNQNFQGLYCKC 148
            |||||.||..|:|.||||||||||||...:..  :|.|.|....|   |..|.||.||.||||.|
  Rat    76 LACSYECHGSHKLFELYTKRNFRCDCGNSKFKNLECKLFPDKSKV---NSCNKYNDNFFGLYCIC 137

  Fly   149 KRPYPDPDRTVEEVMLQCAICEDWFHLPHMKA--PGASDKWLDVCSEMICDGCMDAKPFLKDY-- 209
            |||||||:..|.:.|:||.:||||||..|:.|  |.:.|     ..||:|..||....||..|
  Rat   138 KRPYPDPEDEVPDEMIQCVVCEDWFHGRHLGAIPPESGD-----FQEMVCQSCMRRCSFLWAYAA 197

  Fly   210 ----------------TGLALQPVLEDAKEDKPEADDSQLKNELDRSICDIMKVPEG-------- 250
                            .|:..|.|..     .|..||..|.|.:.....|::|...|
  Rat   198 QLAADGGTACNEVTPRNGVKTQHVTR-----LPAEDDGLLLNAVGMGDQDVIKPANGAHQDKTLK 257

  Fly   251 ESQPDEGEPSQKRAKLD------------------------------DCR----RPKPTKEHQGA 281
            |:.|::|..:.|..|.:                              .||    :.|...:...|
  Rat   258 ENVPEQGRDADKEVKAERNDEPCTSSSSEAHLQTVFKNENIKTEPQSGCRLQELQAKQFLKKDAA 322

  Fly   282 AFWTNDWRKSLCQCSECLSLYKELAVEFLLDVEDSAKTYEERGMKRAEENSSYEQGIRALASIDR 346
            .:|..:||..||.|.:|:.:|.:|.|.||.|..|:...||.:| |..:.....:..:..|:|::|
  Rat   323 TYWPLNWRSRLCTCQDCMKMYGDLDVLFLTDECDTVLAYENKG-KSDQATDRRDPLMDTLSSMNR 386

  Fly   347 TQQIDAITEYNRMKDKLKEYLQAFAASKKVVTEEDINRFFAGMRNENNANL-GQPYFC 403
            .||::.|.|||.:|.:||:||:.||....||..|||.:||...:::....: |..|:|
  Rat   387 VQQVELICEYNDLKTELKDYLKRFADEGTVVKREDIQQFFEEFQSKKRRRVDGLQYYC 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15141	NP_609837.1	zf-UBR	62..122	CDD:280386	35/61 (57%)
CG15141	NP_609837.1	PHD_UBR7	145..199	CDD:277017	27/55 (49%)
Ubr7	XP_006240537.1	zf-UBR	56..113	CDD:280386	35/60 (58%)
Ubr7	XP_006240537.1	PHD_UBR7	134..185	CDD:277017	27/55 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344860
Domainoid	1	1.000	156	1.000	Domainoid score	I4109
eggNOG	1	0.900	-	-		E1_KOG2752
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11998
Inparanoid	1	1.050	267	1.000	Inparanoid score	I2961
OMA	1	1.010	-	-		QHG55347
OrthoDB	1	1.010	-	-		D1428122at2759
OrthoFinder	1	1.000	-	-		FOG0004989
OrthoInspector	1	1.000	-	-		oto98078
orthoMCL	1	0.900	-	-		OOG6_103861
Panther	1	1.100	-	-	LDO	PTHR13513
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3524
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770