Protein Alignment CLIP-190 and tip1

DIOPT Version :9

• Sequence 1: NP_001368962.1
• Gene: CLIP-190 / 35042
• FlyBaseID: FBgn0020503
• Length: 1795
• Species: Drosophila melanogaster
• Sequence 2: NP_593613.1
• Gene: tip1 / 2543044
• PomBaseID: SPAC3C7.12
• Length: 461
• Species: Schizosaccharomyces pombe
• Alignment Length: 659
• Identity: 134/659 - (20%)
• Similarity: 223/659 - (33%)
• Gaps: 261/659 - (39%)

  Fly   239 VGDRVIVSSGFGSRPGILRYLGETQFAPGNWCGVELDEPS----GKNDGTVDDIRYFECK--PKY 297
            :|..|.|.:|   ..|.:||.||.:...|.:.|:|| .|.    |||.|.||...||:.|  .|.
pombe     4 LGSVVEVITG---ERGFVRYAGEVENRKGVYVGLEL-LPEFAEFGKNRGVVDGREYFKTKNNEKT 64

  Fly   298 GVFVPIAK------VSLSPSSKKTRLSRTGSRESL------------TSIGTMNSIATTATSRMR 344
            |:|||..|      :|.|||.|     ..|:..|:            :||..:.::  :::|.:.
pombe    65 GIFVPFDKCKLASSISSSPSPK-----IDGTAASIGMGFPPMSPNLQSSIPRLTNV--SSSSNLS 122

  Fly   345 MNAQQRKSSTPVKPILATPKSQFSMQDLLREKQQHVEKLMVERDLDREDAQNQALQLQKNINEVI 409
            ||.....:.||.:.||     |..::|||.|:|.|.::|        |:......|||..:..
pombe   123 MNTISSTALTPTEKIL-----QKRIEDLLYERQNHQQQL--------EEVLATVDQLQSLVTN-- 172

  Fly   410 IFTDTMYAPLPYADRSRPYRPSKKSRVKVPQQQHIWVPTTLSSSITTSTSTRPTIAAATAAAAAA 474
             |.|                          ||..:   ..|...||.
pombe   173 -FND--------------------------QQDEV---DELRERITL------------------ 189

  Fly   475 AACNRQPLQQQQQPHLHQKQQQAKPKKVWFCDKKKLFPLKARIVELESALDNERKKTEELQCSID 539
                       ::..:.|.:.:|..::         |..|..|..||
pombe   190 -----------KEERIQQMRNEASQRR---------FEFKTTIECLE------------------ 216

  Fly   540 EAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMTI 604
                  :..|...:.|:.:|.:||:::...:|.            .|:|..|          .::
pombe   217 ------ESSNRAIETYENRIAELEAQLEMYMSG------------KSEDDLL----------FSL 253

  Fly   605 QQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFS--------LSECGIENL 661
            ||           |.:..|.: |:.|.|::.||..:..:...|.||.|        |:....|:.
pombe   254 QQ-----------ERDYALNQ-VEILQERVDTLMKQKANSSTANEKLSHMESSSPTLTNASFESP 306

  Fly   662 RRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQ 726
            :|.    |..|:......|...|.:..|..:||||  .:::.|:|.||.
pombe   307 KRG----KGSNDLPENHPQRRQTLEFYEIEIEVLR--EKVEKLQALSDE---------------- 349

  Fly   727 TEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQ 791
                 :|..|.:|.:.||                                   :.:...|.|.|:
pombe   350 -----KDFYISKLEKSLD-----------------------------------RNDTTPVPSDEK 374

  Fly   792 AAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQK-KQ 855
            .:....:||.|..:||:|              |:.|.|:.:..|...::::..:.|||..|: ::
pombe   375 LSNYAAEKENLVSRISEL--------------EHTIEQLTINNERDNERMSPAEFELETTQEVEE 425

  Fly   856 SESEVHLQE 864
            ::|:.|..|
pombe   426 NDSDSHDDE 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLIP-190	NP_001368962.1	PHA03307	<2..>118	CDD:223039
		CAP_GLY	125..189	CDD:396049
		CAP_GLY	239..306	CDD:396049	29/78 (37%)
		SMC_prok_B	<546..912	CDD:274008	63/328 (19%)
		Smc	734..1591	CDD:224117	24/132 (18%)
		SHE3	1502..1702	CDD:293683
		CLIP1_ZNF	1773..1789	CDD:406934
tip1	NP_593613.1	CAP_GLY	4..74	CDD:214997	29/73 (40%)
		FliE	101..>187	CDD:298840	26/132 (20%)
		BBP1_C	<140..238	CDD:291921	30/199 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5244
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1398
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840