DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lrch and AT4G28650

DIOPT Version :9

Sequence 1:	NP_609834.2	Gene:	Lrch / 35041	FlyBaseID:	FBgn0032633	Length:	1135	Species:	Drosophila melanogaster
Sequence 2:	NP_194594.1	Gene:	AT4G28650 / 828983	AraportID:	AT4G28650	Length:	1013	Species:	Arabidopsis thaliana

Alignment Length:	968	Identity:	199/968 - (20%)
Similarity:	331/968 - (34%)	Gaps:	306/968 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SGIGHAGNTSSSTS--SALLSHSQLTRSLERILEEA------------HFSGELILTNRK---LK 87
            :|:...|..|.|.|  |:|:|.:......|.:|.::            .|||.|.|.:.:   |.
plant    79 AGMNLTGKISDSISQLSSLVSFNISCNGFESLLPKSIPPLKSIDISQNSFSGSLFLFSNESLGLV 143

  Fly    88 DFPRTGTKYS--LTDTV-------IADLSRNRF-------------------------AELPEEV 118
            ....:|...|  ||:.:       :.||..|.|                         .|||..:
plant   144 HLNASGNNLSGNLTEDLGNLVSLEVLDLRGNFFQGSLPSSFKNLQKLRFLGLSGNNLTGELPSVL 208

  Fly   119 TTFAFLETLLLYHNTIRS-IPESVKQLSSLTYLDLRSNQLS-SLPREICFL-PLQVLLVSNNRLT 180
            .....|||.:|.:|..:. ||.....::||.||||...:|| .:|.|:..| .|:.||:..|..|
plant   209 GQLPSLETAILGYNEFKGPIPPEFGNINSLKYLDLAIGKLSGEIPSELGKLKSLETLLLYENNFT 273

  Fly   181 -SLPDELGRLDQTLTDLDASYNQL-ANLPARLGELRSLRSLSLRSNHLL-YLPRELTCLSLIS-L 241
             ::|.|:|.: .||..||.|.|.| ..:|..:.:|::|:.|:|..|.|. .:|..::.|:.:. |
plant   274 GTIPREIGSI-TTLKVLDFSDNALTGEIPMEITKLKNLQLLNLMRNKLSGSIPPAISSLAQLQVL 337

  Fly   242 DVSNNKIA-SLPLEIRHMSTLVELQLENNPLTSP-PASLCMRG-LVHVFKFLET-----QAT--- 295
            ::.||.:: .||.::...|.|..|.:.:|..:.. |::||.:| |..:..|..|     .||
plant   338 ELWNNTLSGELPSDLGKNSPLQWLDVSSNSFSGEIPSTLCNKGNLTKLILFNNTFTGQIPATLST 402

  Fly   296 -------KDEKGSRSGGNYDGYTTLRRAPRHNSSGNVLEASTTGS------------TNNQRRHQ 341
                   :.:....:|....|:..|.:..|...:||.|.....|.            :.||.|..
plant   403 CQSLVRVRMQNNLLNGSIPIGFGKLEKLQRLELAGNRLSGGIPGDISDSVSLSFIDFSRNQIRSS 467

  Fly   342 VDSGYNTSDGL------DKRWSHDAPTKSKTDSPLHCVSNSTAATLPRTLPSAVHSQADLMDASL 400
            :.|...:...|      |...|.:.|.:.: |.|.....:.::.||..|:||::.|...|:..:|
plant   468 LPSTILSIHNLQAFLVADNFISGEVPDQFQ-DCPSLSNLDLSSNTLTGTIPSSIASCEKLVSLNL 531

  Fly   401 TSSTST-------------------------IVDESLTLSPTASPCKLSYAHSNSSSNGSSPDQD 440
            .::..|                         ::.||:..||......:||    :...|..|
plant   532 RNNNLTGEIPRQITTMSALAVLDLSNNSLTGVLPESIGTSPALELLNVSY----NKLTGPVP--- 589

  Fly   441 DDIMLDHQERTVHHANGRSGKGL--GNIQTYKEYKEALKQQ---RNQEI---------------- 484
                ::...:|::..:.|...||  |.:....:::.|....   ..:.|
plant   590 ----INGFLKTINPDDLRGNSGLCGGVLPPCSKFQRATSSHSSLHGKRIVAGWLIGIASVLALGI 650

  Fly   485 ------SVYKQKHPNANHSPNDDEDLSPSPPSISNG------SSSNTLPKSIMK----------- 526
                  ::||:.:                    |||      :|....|..:|.
plant   651 LTIVTRTLYKKWY--------------------SNGFCGDETASKGEWPWRLMAFHRLGFTASDI 695

  Fly   527 ----QNSNQIGHNGNGNGSANGNGVDDVVIPKKPIQKVIPSRITEIKP--ASTSDIRSANSSDCL 585
                :.||.||....|            ::.|..:.:  .|.:..:|.  .|.:||....:.|.:
plant   696 LACIKESNMIGMGATG------------IVYKAEMSR--SSTVLAVKKLWRSAADIEDGTTGDFV 746

  Fly   586 GYVKPQSPMK-------------------------NGT--SKFNTSNGGGVQTTVGIVSSTTIKS 623
            |.|.....::                         ||.  ...:..|..| :..|..||...|
plant   747 GEVNLLGKLRHRNIVRLLGFLYNDKNMMIVYEFMLNGNLGDAIHGKNAAG-RLLVDWVSRYNI-- 808

  Fly   624 PVSSTTKLGTVK-------------THRSVTWNH-----DIPAEKLSFTMRREFDRQREETELMS 670
                  .||...             .||.:..|:     ::.|....|.:.|...|::|...:::
plant   809 ------ALGVAHGLAYLHHDCHPPVIHRDIKSNNILLDANLDARIADFGLARMMARKKETVSMVA 867

  Fly   671 QLRTIIETRLKMTLPVD-IASALTDGVILCHLANYVRPRSVASIHVPSPGVNKLTMARCRRNV-D 733
            .....|......||.|| .....:.||:|..|....||..      |..|.:...:...||.: |
plant   868 GSYGYIAPEYGYTLKVDEKIDIYSYGVVLLELLTGRRPLE------PEFGESVDIVEWVRRKIRD 926

  Fly   734 NF-LEA--------CRRIGVDEE--------LIC---------SCEDVVPQIEPQQPQ 765
            |. ||.        ||.  |.||        |:|         |..||:..:...:|:
plant   927 NISLEEALDPNVGNCRY--VQEEMLLVLQIALLCTTKLPKDRPSMRDVISMLGEAKPR 982

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lrch	NP_609834.2	LRR_8	124..179	CDD:290566	22/57 (39%)
		LRR_4	124..161	CDD:289563	15/38 (39%)
		leucine-rich repeat	124..146	CDD:275380	7/22 (32%)
		leucine-rich repeat	147..167	CDD:275380	9/20 (45%)
		leucine-rich repeat	169..192	CDD:275380	8/23 (35%)
		leucine-rich repeat	193..215	CDD:275380	8/22 (36%)
		leucine-rich repeat	216..237	CDD:275380	6/21 (29%)
		leucine-rich repeat	238..260	CDD:275380	5/23 (22%)
		leucine-rich repeat	261..279	CDD:275380	4/18 (22%)
		CH	676..756	CDD:214479	28/107 (26%)
AT4G28650	NP_194594.1	PLN00113	27..986	CDD:215061	199/968 (21%)
		leucine-rich repeat	73..96	CDD:275380	5/16 (31%)
		leucine-rich repeat	97..117	CDD:275380	4/19 (21%)
		leucine-rich repeat	118..141	CDD:275380	5/22 (23%)
		leucine-rich repeat	142..165	CDD:275380	5/22 (23%)
		leucine-rich repeat	166..189	CDD:275380	4/22 (18%)
		leucine-rich repeat	190..213	CDD:275380	3/22 (14%)
		leucine-rich repeat	214..237	CDD:275380	7/22 (32%)
		leucine-rich repeat	238..261	CDD:275380	10/22 (45%)
		leucine-rich repeat	262..285	CDD:275380	8/23 (35%)
		leucine-rich repeat	286..333	CDD:275380	15/46 (33%)
		leucine-rich repeat	334..354	CDD:275380	5/19 (26%)
		leucine-rich repeat	358..381	CDD:275380	6/22 (27%)
		leucine-rich repeat	382..405	CDD:275380	5/22 (23%)
		leucine-rich repeat	406..429	CDD:275380	3/22 (14%)
		leucine-rich repeat	430..453	CDD:275380	5/22 (23%)
		leucine-rich repeat	454..501	CDD:275380	9/47 (19%)
		leucine-rich repeat	502..525	CDD:275380	6/22 (27%)
		leucine-rich repeat	526..549	CDD:275380	3/22 (14%)
		leucine-rich repeat	550..573	CDD:275380	3/22 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910