DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lrch and Sur-8

DIOPT Version :9

Sequence 1:NP_609834.2 Gene:Lrch / 35041 FlyBaseID:FBgn0032633 Length:1135 Species:Drosophila melanogaster
Sequence 2:NP_001262665.1 Gene:Sur-8 / 42093 FlyBaseID:FBgn0038504 Length:694 Species:Drosophila melanogaster


Alignment Length:664 Identity:157/664 - (23%)
Similarity:256/664 - (38%) Gaps:185/664 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 HSVAVGVGSAAGSAIGSGSASLPGSGTGSGSGIGHAGNTSSST---------------------- 52
            :|.|.|.|.|.||   :||...|   ||| :|..|..|.:::.                      
  Fly    79 NSPANGAGGATGS---TGSGQQP---TGS-NGHSHLHNENNANMPPETRPKMVTVKHPESNKPKP 136

  Fly    53 ----SSALLSHSQLTRSLERILEEAHFSGELILTNRKLKDFPRTGTK-YSLTDTVIADLSRNRFA 112
                |..:.:...:.::|:|..:|.  ...|.|:...:...|.|..: ..||:..   |..|:..
  Fly   137 TTKKSKPIQADQDVIKALQRCRDEG--IKRLDLSKSSITVIPSTVKECVHLTELY---LYSNKIG 196

  Fly   113 ELPEEVTTFAFLETLLLYHNTIRSIPESVKQLSSLTYLDLRSNQLSSLPREICFL-PLQVLLVSN 176
            :||.|:.....|..|.|..|::.|:|||::..|.|..||||.|:|:.:|..|..| .|..|.:..
  Fly   197 QLPPEIGCLVSLRNLALNENSLTSLPESLQNCSQLKVLDLRHNKLAEIPPVIYRLRSLTTLYLRF 261

  Fly   177 NRLTSLPDELGRLDQTLTDLDASYNQLANLPARLGELRSLRSLSLRSNHLLYLPREL-TCLSLIS 240
            ||:|::.|:|.:| ..||.|....|::..|.:.:|.|.:|.:|.:..|||.:||.:: .|::|.:
  Fly   262 NRITAVADDLRQL-VNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLEHLPEDIGNCVNLSA 325

  Fly   241 LDVSNNKIASLPLEIRHMSTLVELQLENNPLTSPPASLCMRGLVHVFKFLETQATKDEKGSRSGG 305
            ||:.:|::..:|..|.::.:||.|.:..|.|:|.||:            |:...:.||......|
  Fly   326 LDLQHNELLDIPDSIGNLKSLVRLGMRYNRLSSVPAT------------LKNCKSMDEFNVEGNG 378

  Fly   306 ----------NYDGYTTLRRAPRHNSSGNVLEASTTGS----TN----NQRRHQVDS---G-YNT 348
                      :..|.||:      ..|.|...:..||.    ||    |...:::|.   | ::.
  Fly   379 ITQLPDGMLASLSGLTTI------TLSRNQFASYPTGGPAQFTNVYSINLEHNRIDKIPYGIFSR 437

  Fly   349 SDGLDKRWSHDAPTKSKTDSPLHCVSNSTAATLPRTLPSAVHSQADLMDASL-TSSTSTIVDESL 412
            :.||.|               |:...|...|     ||..:.:..::::.:| |::...:.|:.:
  Fly   438 AKGLTK---------------LNMKENMLTA-----LPLDIGTWVNMVELNLATNALQKLPDDIM 482

  Fly   413 TLSPTASPCKLSYAHSNSSSNGSSPDQDDDI----MLDHQERTVH---HANG------------- 457
            .|.      .|.....:::.....|:...::    :||.:|..:.   |..|             
  Fly   483 NLQ------NLEILILSNNMLKKIPNTIGNLRKLRILDLEENRIEVLPHEIGLLHELQRLILQTN 541

  Fly   458 ------RSGKGLGNIQTYKEYKEALKQQRNQEI-------SVYKQKHPNANHSP----------- 498
                  ||...|||: |:....|...|...:||       ::|..::|.....|           
  Fly   542 QITMLPRSIGHLGNL-THLSVSENNLQFLPEEIGSLESLENLYINQNPGLEKLPFELALCQNLKY 605

  Fly   499 -NDDE-DLSPSPPSISNGSSSNTL-------PKSIMK---------------------QNSNQI- 532
             |.|: .||..||.|..|..|..|       |...|                      |..||. 
  Fly   606 LNIDKCPLSTIPPEIQAGGPSLVLQWLKMHSPYRQMXDVDGVWRTVYVGSDCYYQYELQTVNQAP 670

  Fly   533 GHNGNGNGSANGNG 546
            |..|||.|.|...|
  Fly   671 GAGGNGGGGAAAAG 684

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LrchNP_609834.2 LRR_8 124..179 CDD:290566 22/55 (40%)
LRR_4 124..161 CDD:289563 16/36 (44%)
leucine-rich repeat 124..146 CDD:275380 8/21 (38%)
leucine-rich repeat 147..167 CDD:275380 9/19 (47%)
leucine-rich repeat 169..192 CDD:275380 8/22 (36%)
leucine-rich repeat 193..215 CDD:275380 7/21 (33%)
leucine-rich repeat 216..237 CDD:275380 8/21 (38%)
leucine-rich repeat 238..260 CDD:275380 6/21 (29%)
leucine-rich repeat 261..279 CDD:275380 8/17 (47%)
CH 676..756 CDD:214479
Sur-8NP_001262665.1 leucine-rich repeat 163..184 CDD:275380 4/20 (20%)
leucine-rich repeat 185..207 CDD:275380 7/24 (29%)
LRR_RI 204..401 CDD:238064 64/215 (30%)
LRR_8 207..264 CDD:290566 22/56 (39%)
leucine-rich repeat 208..230 CDD:275380 8/21 (38%)
leucine-rich repeat 231..253 CDD:275380 10/21 (48%)
LRR_8 252..310 CDD:290566 18/58 (31%)
leucine-rich repeat 254..276 CDD:275380 8/22 (36%)
leucine-rich repeat 277..299 CDD:275380 7/21 (33%)
LRR_8 299..356 CDD:290566 18/56 (32%)
leucine-rich repeat 300..322 CDD:275380 8/21 (38%)
leucine-rich repeat 323..345 CDD:275380 6/21 (29%)
LRR_8 344..403 CDD:290566 17/76 (22%)
leucine-rich repeat 346..368 CDD:275380 9/33 (27%)
leucine-rich repeat 369..392 CDD:275380 3/22 (14%)
LRR_RI <379..566 CDD:238064 38/219 (17%)
leucine-rich repeat 417..440 CDD:275380 3/22 (14%)
leucine-rich repeat 441..486 CDD:275380 11/70 (16%)
LRR_8 463..520 CDD:290566 9/62 (15%)
leucine-rich repeat 487..507 CDD:275380 2/19 (11%)
leucine-rich repeat 510..532 CDD:275380 5/21 (24%)
LRR_8 532..588 CDD:290566 11/56 (20%)
leucine-rich repeat 556..578 CDD:275380 5/22 (23%)
leucine-rich repeat 603..626 CDD:275380 8/22 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45467273
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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