Protein Alignment ApepP and APP1

DIOPT Version :10

• Sequence 1: NP_477409.1
• Gene: ApepP / 35029
• FlyBaseID: FBgn0026150
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001328936.1
• Gene: APP1 / 829829
• AraportID: AT4G36760
• Length: 652
• Species: Arabidopsis thaliana
• Alignment Length: 653
• Identity: 251/653 - (38%)
• Similarity: 382/653 - (58%)
• Gaps: 58/653 - (8%)

  Fly     6 TQILTRLRELMLRAQVGDSCGISAYIVPSDDAHQSEYQCQHDERRSFVSGFDGSAGTAVITTETA 70
            ::||:.||.||    ...|..:.|.:|||:|.|||||....|:||.|||||.||||.|:||.:.|
plant     2 SEILSSLRSLM----ASHSPPLDALVVPSEDYHQSEYVSARDKRREFVSGFSGSAGLALITKKEA 62

  Fly    71 LLWTDGRYYQQAEKQLDSNWVLMRDGLSATPSIGAWLAKNLPKGSFVGVDPRLLSFRVWKPIETE 135
            .|||||||:.||.:||...|.|||.|  ..|.:..|::.|||:.:.:|||...:|..........
plant    63 RLWTDGRYFLQALQQLSDEWTLMRMG--EDPLVEVWMSDNLPEEANIGVDSWCVSVDTANRWGKS 125

  Fly   136 LSSAECQLVPIEGNLIDEVWGEDQPPQTSNKIITLKLEHSGVTIAKKWDVVRQQLKEKNADALVV 200
            .:....:|:....:|:|||| :.:||...:.::...||.:|.:::.|::.:|.:||::.|..||:
plant   126 FAKKNQKLITTTTDLVDEVW-KSRPPSEMSPVVVHPLEFAGRSVSHKFEDLRAKLKQEGARGLVI 189

  Fly   201 SALDEIAWFLNLRGSDIDFNPVFFSYLIVTNDELLLFVDSGKLPTDFVQHQKENNVQISVLPYAS 265
            :||||:||..|:||:|:.:.||..::.|:|.|...|:||..|:..:  .:...|.:.:.|..|..
plant   190 AALDEVAWLYNIRGTDVAYCPVVHAFAILTTDSAFLYVDKKKVSDE--ANSYFNGLGVEVREYTD 252

  Fly   266 IGIEISKIVSTR------------------------ESKIWIAPTS-SYYLTALIPKSRRIQEVT 305
            :..:::.:.|.|                        ..::|:.|.| .|.|.:.:...:.:.:.:
plant   253 VISDVALLASDRLISSFASKTVQHEAAKDMEIDSDQPDRLWVDPASCCYALYSKLDAEKVLLQPS 317

  Fly   306 PICVLKAIKNDVEIAGFINSHIRDGVALCQYFAWLEDQVNK--GA------------------EV 350
            ||.:.||:||.||:.|..|:|:|||.|:.||..||::|:.:  ||                  ::
plant   318 PISLSKALKNPVELEGIKNAHVRDGAAVVQYLVWLDNQMQELYGASGYFLEAEASKKKPSETSKL 382

  Fly   351 DEMSGADKLESFRSTKDKYMGLSFTTISASGPNGSVIHYHPKKETNRKINDKEIYLCDSGAQYLD 415
            .|::.:|||||.|::|:.:.||||.|||:.|.|.:||||.|:.|...:::..:||||||||||||
plant   383 TEVTVSDKLESLRASKEHFRGLSFPTISSVGSNAAVIHYSPEPEACAEMDPDKIYLCDSGAQYLD 447

  Fly   416 GTTDVTRTLHFGEPTEFQKEAYTRVLKGQLSFGSTVFPAKVKGQVLDTLARKALWDVGLDYGHGT 480
            ||||:|||:|||:|:..:||.||.|.||.::.|:..||....|..||.|||..||..||||.|||
plant   448 GTTDITRTVHFGKPSAHEKECYTAVFKGHVALGNARFPKGTNGYTLDILARAPLWKYGLDYRHGT 512

  Fly   481 GHGVGHFLNVHEGPMGVGIRLMPDDPGLQANMFISNEPGFYQDGEFGIRVEDIVQIVPGQVAHNF 545
            |||||.:|.|||||..|..|....:..|||.|.:::|||:|:||.||||:|:::.:...:...||
plant   513 GHGVGSYLCVHEGPHQVSFRPSARNVPLQATMTVTDEPGYYEDGNFGIRLENVLVVNDAETEFNF 577

  Fly   546 SNRGALTFKTITMCPKQTKMIKKELLSDAEVKLLNSYHQQVWDTLSPILSREGDEFTLSWLKKEV 610
            .::|.|.|:.||..|.|.|:|..:.|:..|:..||:||.:..|.|:|.:    ::..:.||||..
plant   578 GDKGYLQFEHITWAPYQVKLIDLDELTREEIDWLNTYHSKCKDILAPFM----NQTEMEWLKKAT 638

  Fly   611 QPI 613
            :|:
plant   639 EPL 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ApepP	NP_477409.1	Creatinase_N	9..154	CDD:460159	60/144 (42%)
		Creatinase_N_2	158..318	CDD:465053	47/184 (26%)
		APP	321..545	CDD:238518	113/243 (47%)
		Peptidase_M24_C	551..613	CDD:465052	21/61 (34%)
APP1	NP_001328936.1	Creatinase_N	5..144	CDD:460159	60/144 (42%)
		Creatinase_N_2	148..330	CDD:465053	47/183 (26%)
		APP	333..578	CDD:238518	114/244 (47%)
		Peptidase_M24_C	581..641	CDD:465052	22/63 (35%)