Protein Alignment ApepP and CG6225

DIOPT Version :10

• Sequence 1: NP_477409.1
• Gene: ApepP / 35029
• FlyBaseID: FBgn0026150
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_650221.1
• Gene: CG6225 / 41559
• FlyBaseID: FBgn0038072
• Length: 704
• Species: Drosophila melanogaster
• Alignment Length: 636
• Identity: 197/636 - (30%)
• Similarity: 327/636 - (51%)
• Gaps: 58/636 - (9%)

  Fly     9 LTRLRELM-LRAQVGDSCGISAYIVPSDDAHQSEYQCQHDERRSFVSGFDGSAGTAVITTETALL 72
            |..:||.| :||.: ....|..||:||.|.|.::.....|:|..::|||.|....|.:|:..|.:
  Fly    52 LMAMREQMQIRATL-QGPEIYGYILPSTDEHLNQEVAARDQRLRYLSGFSGVRAFAAVTSHGAAI 115

  Fly    73 WTDGRYYQQAEKQLDSNWVLMRDGLSATPSIGAWLAKNLPKGSFVGVDPRLLSFRVWKPIETELS 137
            |.:.||.|||:.:|:.:|.:..  .|...|:..||..::.....||.||.|:...:|...|.||.
  Fly   116 WVENRYAQQADGELECDWEIYL--TSGNVSVADWLGSHVHIDKRVGADPHLVPHSLWVQWERELE 178

  Fly   138 SAECQLVPIEGNLIDEVWGEDQPPQTSNKIITLKLEH-SGVTIAKKWDVVRQQLKEKNADALVVS 201
            ....:||.|..||:|.:||:::|....|::|.:..:| :|.:...|...:|::|.....||:||:
  Fly   179 DKFLKLVRINTNLVDHIWGDERPEMPKNQVIKVHEKHFAGESWQDKVKELRRRLAHLGCDAMVVT 243

  Fly   202 ALDEIAWFLNLRGSDIDFNPVFFSYLIVTNDELLLFVDSGKLPTDFVQHQKE---NNVQISVLPY 263
            :|.|||:.||:||:||.:.||..||.:::.|::..:||..|:......|.:.   |...:.:..|
  Fly   244 SLTEIAYLLNIRGTDIPYTPVIKSYAVISRDDIFFYVDHSKISLGIDLHLRTDCFNEDCVKIKEY 308

  Fly   264 ASIGIEISKIVSTRESKIW---IAPT-------SSYYLTALIPKSRRIQEVTPICVLKAIKNDVE 318
            ..|..:|...     ::||   :.|.       :|..:...:|....:.|::||..::|.||..|
  Fly   309 NQIWSDIRTY-----AQIWKRVLVPAPCVQDLGASEAIYTSMPGKIVVWEISPIIFMRAQKNSDE 368

  Fly   319 IAGFINSHIRDGVALCQYFA----------WLEDQVNKGAEVDEMSGADKLESFRSTKDKYMGLS 373
            .||...:|||||.|:|:..:          |.|:::..           ::|.:|.::....|||
  Fly   369 QAGMRRAHIRDGAAICEAMSNMETRFHTEQWTEEKIKY-----------EVELWRLSQKHAKGLS 422

  Fly   374 FTTISASGPNGSVIHYHPKKETNRKINDKEIYLCDSGAQYLDGTTDVTRTLHFGEPTEFQKEAYT 438
            ..|:.|.|.:.::.:|.....||.:::|:.:.:.:||.|||:|||||:||..|||||...|:|||
  Fly   423 LRTVVAYGEHSALPYYISSNVTNIEVSDQSLLVIESGGQYLEGTTDVSRTFIFGEPTHEMKKAYT 487

  Fly   439 RVLKGQLSFGSTVFPAKVKGQVLDTLARKALWDVGLDYGHGTGHGVGHFLNVHEGPMGVGIRLMP 503
            .||.|.|......||:.:|...:|.|.|..:|....|:...||||:|.|.:|.|.|:.|..
  Fly   488 NVLAGILHLAQLKFPSDLKPSEVDALVRSMVWKDMTDFPQATGHGIGSFGSVEEPPISVSY---- 548

  Fly   504 DDPGLQANM------FISNEPGFYQDGEFGIRVEDIVQIVPGQVAHNFSNRGALTFKTITMCPKQ 562
               |..::.      |.|:|.|:|:..:||:|:::::::|.....|. |....|.|:.:||.|.:
  Fly   549 ---GKNSSFHFKQGYFFSSESGYYKRDDFGVRLKNVLEVVDTGHTHP-SGARFLAFRDVTMVPYE 609

  Fly   563 TKMIKKELLSDAEVKLLNSYHQQVWDTLSPILSREGDEFTLSWLKKEVQPI 613
            .|:|...|||.||.:|||.|:.::.:.:...|.|.|:.....|:..:.:.|
  Fly   610 PKLIDSTLLSAAEKRLLNEYNAKIRNDIGDELKRLGNMRAFYWMMNQTRHI 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ApepP	NP_477409.1	Creatinase_N	9..154	CDD:460159	49/145 (34%)
		Creatinase_N_2	158..318	CDD:465053	46/173 (27%)
		APP	321..545	CDD:238518	76/239 (32%)
		Peptidase_M24_C	551..613	CDD:465052	20/61 (33%)
CG6225	NP_650221.1	Creatinase_N	89..195	CDD:480631	36/107 (34%)
		Creatinase_N_2	199..368	CDD:465053	46/173 (27%)
		APP	371..594	CDD:238518	76/241 (32%)
		Peptidase_M24_C	597..660	CDD:465052	20/62 (32%)