Protein Alignment ApepP and xpnpep1

DIOPT Version :9

• Sequence 1: NP_001246053.1
• Gene: ApepP / 35029
• FlyBaseID: FBgn0026150
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: XP_021324983.1
• Gene: xpnpep1 / 406253
• ZFINID: ZDB-GENE-040426-999
• Length: 625
• Species: Danio rerio
• Alignment Length: 618
• Identity: 298/618 - (48%)
• Similarity: 408/618 - (66%)
• Gaps: 13/618 - (2%)

  Fly     5 TTQILTRLRELMLRAQVGDSCGISAYIVPSDDAHQSEYQCQHDERRSFVSGFDGSAGTAVITTET 69
            |.::|.:||:.|..::.... .|.||||||.|||||||....|.||.|:.||:||||||::|.:.
Zfish    11 TVELLRQLRQAMKNSKYITE-PIQAYIVPSGDAHQSEYIAPCDCRREFICGFNGSAGTAIVTEQH 74

  Fly    70 ALLWTDGRYYQQAEKQLDSNWVLMRDGLSATPSIGAWLAKNLPKGSFVGVDPRLLSFRVWKPIET 134
            |.|||||||:.||.:|:|:||.||:.||..|||...||...||:.|.|||||.:::...||.:..
Zfish    75 AALWTDGRYFLQASQQMDNNWTLMKMGLKETPSQEDWLISVLPENSKVGVDPWIIAADQWKNMSK 139

  Fly   135 ELSSAECQLVPIEGNLIDEVWGEDQPPQTSNKIITLKLEHSGVTIAKKWDVVRQQLKEKNADALV 199
            .||.|...||.::.||||.:| ||:|.:.|.|:..|.|:::|.|...|...:|.::.|:.....|
Zfish   140 ALSGAGHSLVAVQDNLIDAIW-EDRPSRPSTKLTALALKYTGFTWQDKITTLRGKMSERKISWFV 203

  Fly   200 VSALDEIAWFLNLRGSDIDFNPVFFSYLIVTNDELLLFVDSGKLPTDFVQHQKE------NNVQI 258
            |:|||||||..|||||||::|||||:|.|:..:.:.|||||.:|....::...|      .::.:
Zfish   204 VTALDEIAWLFNLRGSDIEYNPVFFAYAIIGMNSIRLFVDSKRLSDPAIREHLELDSPSKPDLSV 268

  Fly   259 SVLPYASIGIEISKIVSTRE--SKIWIAPTSSYYLTALIPKSRRIQ-EVTPICVLKAIKNDVEIA 320
            ...||.|:..|:..:.:..|  .|:||...:|..||..||||.|.. ..||:|:.||:||..||.
Zfish   269 QCFPYESVYTELQAVCAALEPKDKMWICDKASCALTQAIPKSHRSAIPYTPLCLAKAVKNATEIQ 333

  Fly   321 GFINSHIRDGVALCQYFAWLEDQVNKGAEVDEMSGADKLESFRSTKDKYMGLSFTTISASGPNGS 385
            |...:||:|.||||:.|||||.::.||. |.|:|.|||.|..||.:.:::||||.|||:.||||:
Zfish   334 GMKMAHIKDAVALCELFAWLEKEIPKGT-VTEISAADKAEELRSQQKEFVGLSFPTISSVGPNGA 397

  Fly   386 VIHYHPKKETNRKINDKEIYLCDSGAQYLDGTTDVTRTLHFGEPTEFQKEAYTRVLKGQLSFGST 450
            :|||.|..||||.::..|:||.||||||.|||||||||:|||.|:|::||.:|.||||.::..:.
Zfish   398 IIHYRPLPETNRTLSLNEVYLIDSGAQYTDGTTDVTRTVHFGTPSEYEKECFTYVLKGHIAVSAA 462

  Fly   451 VFPAKVKGQVLDTLARKALWDVGLDYGHGTGHGVGHFLNVHEGPMGVGIRLMPDDPGLQANMFIS 515
            |||...||.:||:.||.||||.||||.||||||||.||||||||.|:..:...|:| |:|.|.:|
Zfish   463 VFPNGTKGHLLDSFARAALWDSGLDYLHGTGHGVGCFLNVHEGPCGISYKTFADEP-LEAGMIVS 526

  Fly   516 NEPGFYQDGEFGIRVEDIVQIVPGQVAHNFSNRGALTFKTITMCPKQTKMIKKELLSDAEVKLLN 580
            :|||:|:||.||||:|::|.:||....:|:.|||:|||:.:|:.|.|.|||..:||:..|...:|
Zfish   527 DEPGYYEDGSFGIRLENVVLVVPATTKYNYRNRGSLTFEPLTLVPIQLKMINTDLLTQKERDWVN 591

  Fly   581 SYHQQVWDTLSPILSREGDEFTLSWLKKEVQPI 613
            .||::..:|:...|.|:|.:....||.:|.|||
Zfish   592 DYHRKCRETIGAELERQGRKEARDWLIRETQPI 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ApepP	NP_001246053.1	Creatinase_N	9..154	CDD:307473	73/144 (51%)
		Creatinase_N_2	158..318	CDD:318430	64/168 (38%)
		APP	321..545	CDD:238518	127/223 (57%)
		Peptidase_M24_C	551..613	CDD:318429	23/61 (38%)
xpnpep1	XP_021324983.1	Creatinase_N	15..159	CDD:329087	73/144 (51%)
		Creatinase_N_2	162..331	CDD:318430	64/168 (38%)
		APP	334..555	CDD:238518	127/222 (57%)
		Peptidase_M24_C	562..624	CDD:318429	23/61 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574088
Domainoid	1	1.000	258	1.000	Domainoid score	I1969
eggNOG	1	0.900	-	-		E1_COG0006
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6424
Inparanoid	1	1.050	582	1.000	Inparanoid score	I979
OMA	1	1.010	-	-		QHG62675
OrthoDB	1	1.010	-	-		D265764at33208
OrthoFinder	1	1.000	-	-		FOG0001510
OrthoInspector	1	1.000	-	-		oto41499
orthoMCL	1	0.900	-	-		OOG6_100896
Panther	1	1.100	-	-	LDO	PTHR43763
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1687
SonicParanoid	1	1.000	-	-		X1075
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800