Protein Alignment ApepP and xpnpep1

DIOPT Version :10

• Sequence 1: NP_477409.1
• Gene: ApepP / 35029
• FlyBaseID: FBgn0026150
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: XP_021324983.2
• Gene: xpnpep1 / 406253
• ZFINID: ZDB-GENE-040426-999
• Length: 625
• Species: Danio rerio
• Alignment Length: 618
• Identity: 297/618 - (48%)
• Similarity: 408/618 - (66%)
• Gaps: 13/618 - (2%)

  Fly     5 TTQILTRLRELMLRAQVGDSCGISAYIVPSDDAHQSEYQCQHDERRSFVSGFDGSAGTAVITTET 69
            |.::|.:||:.|..::.... .|.||||||.|||||||....|.||.|:.||:||||||::|.:.
Zfish    11 TVELLRQLRQAMKNSKYITE-PIQAYIVPSGDAHQSEYIAPCDCRREFICGFNGSAGTAIVTEQH 74

  Fly    70 ALLWTDGRYYQQAEKQLDSNWVLMRDGLSATPSIGAWLAKNLPKGSFVGVDPRLLSFRVWKPIET 134
            |.|||||||:.||.:|:|:||.||:.||..|||...||...||:.|.|||||.:::...||.:..
Zfish    75 AALWTDGRYFLQASQQMDNNWTLMKMGLKETPSQEDWLISVLPENSKVGVDPWIIAADQWKNMSK 139

  Fly   135 ELSSAECQLVPIEGNLIDEVWGEDQPPQTSNKIITLKLEHSGVTIAKKWDVVRQQLKEKNADALV 199
            .||.|...||.::.||||.:| |::|.:.|.|:..|.|:::|.|...|...:|.::.|:.....|
Zfish   140 ALSGAGHSLVAVQDNLIDAIW-ENRPSRPSTKLTALALKYTGFTWQDKITTLRGKMSERKISWFV 203

  Fly   200 VSALDEIAWFLNLRGSDIDFNPVFFSYLIVTNDELLLFVDSGKLPTDFVQHQKE------NNVQI 258
            |:|||||||..|||||||::|||||:|.|:....:.|||||.:|....::...|      .::.:
Zfish   204 VTALDEIAWLFNLRGSDIEYNPVFFAYAIIGMSSIRLFVDSKRLSDPAIREHLELDSPSKPDLSV 268

  Fly   259 SVLPYASIGIEISKIVSTRE--SKIWIAPTSSYYLTALIPKSRRIQ-EVTPICVLKAIKNDVEIA 320
            ...||.|:..|:..:.:..|  .|:||...:|..||..||||.|.. ..||:|:.||:||..||.
Zfish   269 QCFPYESVYTELQAVCAALEPKDKMWICDKASCALTQAIPKSHRSAIPYTPLCLAKAVKNATEIQ 333

  Fly   321 GFINSHIRDGVALCQYFAWLEDQVNKGAEVDEMSGADKLESFRSTKDKYMGLSFTTISASGPNGS 385
            |...:||:|.||||:.|||||.::.||. |.|:|.|||.|..||.:.:::||||.|||:.||||:
Zfish   334 GMKMAHIKDAVALCELFAWLEKEIPKGT-VTEISAADKAEELRSQQKEFVGLSFPTISSVGPNGA 397

  Fly   386 VIHYHPKKETNRKINDKEIYLCDSGAQYLDGTTDVTRTLHFGEPTEFQKEAYTRVLKGQLSFGST 450
            :|||.|..||||.::..|:||.||||||:|||||||||:|||.|:|::||.:|.||||.::..:.
Zfish   398 IIHYRPLPETNRTLSLNEVYLIDSGAQYIDGTTDVTRTVHFGTPSEYEKECFTYVLKGHIAVSAA 462

  Fly   451 VFPAKVKGQVLDTLARKALWDVGLDYGHGTGHGVGHFLNVHEGPMGVGIRLMPDDPGLQANMFIS 515
            |||...||.:||:.||.||||.||||.||||||||.||||||||.|:..:...|:| |:|.|.:|
Zfish   463 VFPNGTKGHLLDSFARAALWDSGLDYLHGTGHGVGCFLNVHEGPCGISYKTFADEP-LEAGMIVS 526

  Fly   516 NEPGFYQDGEFGIRVEDIVQIVPGQVAHNFSNRGALTFKTITMCPKQTKMIKKELLSDAEVKLLN 580
            :|||:|:||.||||:|::|.:||....:|:.|||:|||:.:|:.|.|.|||..:||:..|...:|
Zfish   527 DEPGYYEDGSFGIRLENVVLVVPATTKYNYRNRGSLTFEPLTLVPIQLKMINTDLLTQKERDWVN 591

  Fly   581 SYHQQVWDTLSPILSREGDEFTLSWLKKEVQPI 613
            .||::..:|:...|.|:|.:....||.:|.|||
Zfish   592 DYHRKCRETIGAELERQGRKEARDWLIRETQPI 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ApepP	NP_477409.1	Creatinase_N	9..154	CDD:460159	73/144 (51%)
		Creatinase_N_2	158..318	CDD:465053	63/168 (38%)
		APP	321..545	CDD:238518	127/223 (57%)
		Peptidase_M24_C	551..613	CDD:465052	23/61 (38%)
xpnpep1	XP_021324983.2	None