Protein Alignment ApepP and K12C11.1

DIOPT Version :9

• Sequence 1: NP_001246053.1
• Gene: ApepP / 35029
• FlyBaseID: FBgn0026150
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_490843.1
• Gene: K12C11.1 / 171704
• WormBaseID: WBGene00019673
• Length: 498
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 136/595 - (22%)
• Similarity: 207/595 - (34%)
• Gaps: 229/595 - (38%)

  Fly    68 ETALLWTDGRYYQQAEKQLDSNWVLMRDGLSAT-------PSIGAWLAKNLPKGSFVGVDPRLLS 125
            |:...||.|....:....:|     :|.|...|       ||...|             |.::.:
 Worm    61 ESYFFWTFGVNESEFYGAID-----VRSGGKTTLFAPRLDPSYAIW-------------DGKINN 107

  Fly   126 FRVWKPIETELSSAECQLVPIEGNLIDEVWGEDQPPQTSNKIITLKLEHSGVTIAKKWDVVRQQL 190
            .:.:|                |...:|||...|:....:.|:..|..:|..:            |
 Worm   108 EQFFK----------------EKYAVDEVVFNDKTTTIAEKLKELSAKHVYL------------L 144

  Fly   191 KEKNADALVVSALDEIAWFLNLRGSDIDFNPVFFSYLIVTNDELLLFVDSGKLPTDFVQHQKENN 255
            :.:|.|:..|.|..:.|      ||. ||.          .|..||:.:..:|..  |:.:||
 Worm   145 RAENTDSGDVLAEPKFA------GSG-DFQ----------LDTELLYKEMAELRV--VKTEKE-- 188

  Fly   256 VQISVLPYASIGIEISKIVSTRESKIWIAPTSSYYLTALIPKSRRIQEVTPICVLKAIKNDVEIA 320
              |.|:.||      |||.|                     ::.|          .|:|
 Worm   189 --IGVMRYA------SKIAS---------------------EAHR----------AAMK------ 208

  Fly   321 GFINSHIRDGVALCQYFAWLEDQVNKGAEVDEMSGADKLES-FRSTKDKYMG---LSFTTISASG 381
                 |:|.|  |.:|                     :||| ||.|...:.|   |::|.|:|:|
 Worm   209 -----HMRPG--LYEY---------------------QLESLFRHTSYYHGGCRHLAYTCIAATG 245

  Fly   382 PNGSVIHY-HPKKETNRKINDKEIYLCDSGAQYLDGTTDVTRTL-HFGEPTEFQKEAYTRVLKGQ 444
            .||||:|| |.....::.|.|.::.|.|.|.:|....:|:|.:. ..|:.||.||..|..||...
 Worm   246 CNGSVLHYGHANAPNDKFIKDGDMCLFDMGPEYNCYASDITTSFPSNGKFTEKQKIVYNAVLAAN 310

  Fly   445 LSFGSTVFPAKVKGQVLDTLARKALWD----VGLDYG----------------HGTGHGVGHFLN 489
            |:......|. |:...:..|:.|.:.:    .||..|                ||.||.:|  |:
 Worm   311 LAVLKAAKPG-VRWTDMHILSEKVILEHLKQAGLIVGDIDKAVEARVGAVFMPHGLGHLIG--LD 372

  Fly   490 VHE--GPMG--------VGIRLMPDDPGLQANMFISNEPGFY-------------QDGEF----- 526
            ||:  |.||        .|::.:.....|...|.|:.|||.|             :..||
 Worm   373 VHDCGGYMGDATPRSTLPGLKSLRTTRTLMERMAITIEPGCYFIDFLLNEALADPKKSEFLVKSE 437

  Fly   527 --------GIRVEDIVQIVPGQVAHNFSNRGALTFKTITMCPKQTKMIKKELLSDAE--VKLLNS 581
                    |:|:||.| |:......|.|:           .|:..:.|:..:.|..|  .|::.|
 Worm   438 IDKYRGSGGVRIEDDV-IIRASGNENLSD-----------LPRTVEEIENFMASGGEWTEKVIES 490

  Fly   582 YHQQVWDTLS 591
               :|.|.||
 Worm   491 ---RVSDFLS 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ApepP	NP_001246053.1	Creatinase_N	9..154	CDD:307473	15/92 (16%)
		Creatinase_N_2	158..318	CDD:318430	32/159 (20%)
		APP	321..545	CDD:238518	75/285 (26%)
		Peptidase_M24_C	551..613	CDD:318429	10/43 (23%)
K12C11.1	NP_490843.1	AMP_N	12..152	CDD:198079	24/136 (18%)
		Prolidase	189..465	CDD:238520	87/350 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0006
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810