Protein Alignment ApepP and Xpnpep2

DIOPT Version :9

• Sequence 1: NP_001246053.1
• Gene: ApepP / 35029
• FlyBaseID: FBgn0026150
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_476496.1
• Gene: Xpnpep2 / 117522
• RGDID: 621277
• Length: 674
• Species: Rattus norvegicus
• Alignment Length: 632
• Identity: 266/632 - (42%)
• Similarity: 375/632 - (59%)
• Gaps: 53/632 - (8%)

  Fly     6 TQILTRLRELMLRAQVGDSCGISAYIVPSDDAHQSEYQCQHDERRSFVSGFDGSAGTAVITTETA 70
            |.:.|.:|...||.|: :...:||||:|..|||.|||..:|||||:::|||.|||||||:|.:.|
  Rat    46 TAVNTTMRLAALRQQM-EKSNLSAYIIPDTDAHMSEYIGKHDERRAWISGFTGSAGTAVVTKKKA 109

  Fly    71 LLWTDGRYYQQAEKQLDSNWVLMRDGLSATPSIGAWLAKNLPKGSFVGVDPRLLSFRVWKPIETE 135
            .:|||.||:.|||:|:|.||.|.::  .:..||.||:...:|.|..||.||.|.|...|:..:.|
  Rat   110 AVWTDSRYWTQAERQMDCNWELHKE--VSISSIVAWILAEVPDGENVGFDPFLFSVGSWENYDQE 172

  Fly   136 LSSAECQLVPIEGNLIDEVWGEDQPPQTSNKIITLKLEHSGVTIAKKWDVVRQQLKEKN--ADAL 198
            |..:...|:.|..||:|..||.::||..|..|..|..|.:|.|..:|...:|..::...  ...:
  Rat   173 LQDSNRHLLSITTNLVDVAWGSERPPVPSQPIYALPKEFTGSTWQEKVSAIRSYMQNHTMAPTGV 237

  Fly   199 VVSALDEIAWFLNLRGSDIDFNPVFFSYLIVTNDELLLFVDSGKLPTDFVQH-----------QK 252
            ::|||||.||..|||.|||.:||.|:||.::|:..:.|||:..:...:.:|:           |.
  Rat   238 LLSALDETAWLFNLRSSDIPYNPFFYSYTLLTDSSIRLFVNKSRFSLETLQYLNTNCTLPMCVQL 302

  Fly   253 ENNVQI--SVLPYASIGIEISKIVSTRESKIWIAPTSSYYLTALIPKSRRIQEV-TPICVLKAIK 314
            |:..||  .|..|||..::|         .|.|:.| :|.:..:|||.:.:.|. :|:.::||:|
  Rat   303 EDYSQIRDGVKAYASGNVKI---------LIGISYT-TYGVYDVIPKEKLVTETYSPVMLIKAVK 357

  Fly   315 NDVEIAGFINSHIRDGVALCQYFAWLEDQVNKGAEVDEMSGADKLESFRSTKDKYMGLSFTTISA 379
            |..|.|....||:||.||:.||..|||..|.||. |||.|||:.::..|..::...|.||.||||
  Rat   358 NSKEQALLKASHVRDAVAVIQYLVWLEKNVPKGT-VDEFSGAEHIDQLRRNENFSSGPSFETISA 421

  Fly   380 SGPNGSVIHYHPKKETNRKINDKEIYLCDSGAQYLDGTTDVTRTLHFGEPTEFQKEAYTRVLKGQ 444
            ||.|.::.||.|.||.:||::..|:||.|||.||.|||||:|||:|:|.||.||||||||||.|.
  Rat   422 SGLNAALAHYSPTKELHRKLSLDEMYLVDSGGQYWDGTTDITRTVHWGTPTAFQKEAYTRVLMGN 486

  Fly   445 LSFGSTVFPAKVKGQVLDTLARKALWDVGLDYGHGTGHGVGHFLNVHEGPMGVGIRLMPDDPGLQ 509
            :.....||||...|:|::..||:|||:|||:||||||||:|:||.|||.|:|.....|    .:.
  Rat   487 IDLSRLVFPAATSGRVVEAFARRALWEVGLNYGHGTGHGIGNFLCVHEWPVGFQYNNM----AMA 547

  Fly   510 ANMFISNEPGFYQDGEFGIRVEDIVQIV------PGQVAHNFSNRGALTFKTITMCPKQTKMIKK 568
            ..||.|.|||:|||||||||:||:..:|      ||..         |||:.::..|....:|..
  Rat   548 KGMFTSIEPGYYQDGEFGIRLEDVALVVEAKTKYPGTY---------LTFELVSFVPYDRNLIDV 603

  Fly   569 ELLSDAEVKLLNSYHQQVWDTLSPILSREG--DEFTLSWLKKEVQPI 613
            .|||..:::.||.|:|.:.:.:.|.|.|..  :||  :||::..:|:
  Rat   604 SLLSPEQLQYLNRYYQTIRENIGPELQRRQLLEEF--AWLERHTEPL 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ApepP	NP_001246053.1	Creatinase_N	9..154	CDD:307473	66/144 (46%)
		Creatinase_N_2	158..318	CDD:318430	55/175 (31%)
		APP	321..545	CDD:238518	120/229 (52%)
		Peptidase_M24_C	551..613	CDD:318429	19/63 (30%)
Xpnpep2	NP_476496.1	Creatinase_N	53..177	CDD:307473	60/126 (48%)
		Creatinase_N_2	195..361	CDD:318430	55/175 (31%)
		APP	365..583	CDD:238518	118/222 (53%)
		Peptidase_M24_C	584..648	CDD:318429	19/74 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0006
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62675
OrthoDB	1	1.010	-	-		D265764at33208
OrthoFinder	1	1.000	-	-		FOG0001510
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100896
Panther	1	1.100	-	-	O	PTHR43763
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1075
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.830