Protein Alignment ApepP and xpnpep2

DIOPT Version :9

• Sequence 1: NP_001246053.1
• Gene: ApepP / 35029
• FlyBaseID: FBgn0026150
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: XP_031747549.1
• Gene: xpnpep2 / 100145559
• XenbaseID: XB-GENE-969249
• Length: 705
• Species: Xenopus tropicalis
• Alignment Length: 628
• Identity: 236/628 - (37%)
• Similarity: 366/628 - (58%)
• Gaps: 41/628 - (6%)

  Fly     3 RSTTQILTRLRELMLRAQVGDSCGISAYIVPSDDAHQSEYQCQHDERRSFVSGFDGSAGTAVITT 67
            ::||:.|..||:.|...      .||||||||.|||..||....::||::::||.||:|.||:|.
 Frog    74 KNTTRQLNDLRQKMREN------NISAYIVPSTDAHLGEYTADREKRRNWLTGFTGSSGVAVVTH 132

  Fly    68 ETALLWTDGRYYQQAEKQLDSNWVLMRDGLSATPSIGAWLAKNLPKGSFVGVDPRLLSFRVWKPI 132
            ....::||.||:.|||:::|.||.|.:. ||:. ::..|:.:.|..|..:|.||.|.|...|:..
 Frog   133 TRGAVFTDSRYWIQAEREMDCNWELEKT-LSSY-AVVTWIQQELKPGEGIGFDPFLFSIGEWQSY 195

  Fly   133 ETELSSAECQLVPIEGNLIDEVWGEDQPPQTSNKIITLKLEHSGVTIAKKWDVVRQQLKE--KNA 195
            .:.:.|:......|..||:|.|||..:|...:..|..||.|..|.|..:|...:|.::..  :..
 Frog   196 SSLIQSSGMTFQSIPTNLVDLVWGNQRPSLPNETIYALKDEFVGSTWQEKVSNIRAKMNSHAQKP 260

  Fly   196 DALVVSALDEIAWFLNLRGSDIDFNPVFFSYLIVTNDELLLFVDSGKL-------------PTDF 247
            .|:::|||:|.||..||||.||.:||.|:||.::|.|.:.:||:..::             |:..
 Frog   261 SAVLLSALEETAWLFNLRGQDIPYNPFFYSYTLLTLDSVRIFVNVNRITNEVQTYLNTNCAPSSC 325

  Fly   248 VQHQKENNVQISVLPYASIGIEISKIVSTRESKIWIAPT-SSYYLTALIPKSRRI-QEVTPICVL 310
            ||..:.:.::.::|.|....:           ||||..: :||.:...|||.:.: :|.:|:.:.
 Frog   326 VQLTEYDQLRDTLLEYVKGNV-----------KIWIGQSYTSYGVYETIPKDKLLAEEYSPVLIA 379

  Fly   311 KAIKNDVEIAGFINSHIRDGVALCQYFAWLEDQVNKGAEVDEMSGADKLESFRSTKDKYMGLSFT 375
            ||:|::.|.....:.|:||.||:.||..|||..:.:|. |||:||.|.::|.|..:....|.||.
 Frog   380 KAVKSEKEQKLLKDCHVRDAVAVIQYLVWLEKNLARGL-VDELSGGDYVDSLRQKQQYSKGPSFA 443

  Fly   376 TISASGPNGSVIHYHPKKETNRKINDKEIYLCDSGAQYLDGTTDVTRTLHFGEPTEFQKEAYTRV 440
            ||||||.|.::.||....||.|::...|:||.|||.||.|||||:|||:|:|.||.|:|||||||
 Frog   444 TISASGLNAALAHYRATNETKRELGVNEMYLVDSGGQYFDGTTDITRTVHWGTPTAFEKEAYTRV 508

  Fly   441 LKGQLSFGSTVFPAKVKGQVLDTLARKALWDVGLDYGHGTGHGVGHFLNVHEGPMGVGIRLMPDD 505
            |.|.:.....:||.:..|:::::.||||||:.||:||||||||:|:|.:|||.|:|    ...::
 Frog   509 LMGNIELTRLIFPQRTSGRMIESFARKALWEAGLNYGHGTGHGIGNFFSVHEWPVG----FQSNN 569

  Fly   506 PGLQANMFISNEPGFYQDGEFGIRVEDIVQIVPGQVAHNFSNRGALTFKTITMCPKQTKMIKKEL 570
            ..:...||.|.|||:|.||.||||:||||.||..:.|:.|.....|.|:|:|:.|....:|...:
 Frog   570 IAMTKGMFTSIEPGYYHDGHFGIRIEDIVLIVEAKTAYMFGGEPYLAFETVTLVPYDRNLIDTSI 634

  Fly   571 LSDAEVKLLNSYHQQVWDTLSPILSREGDEFTLSWLKKEVQPI 613
            :.|.:::.::.|::::.|.:.|.|.::.......||:|..:|:
 Frog   635 MQDVQIEYVDQYYKKIKDLVGPELQKQNLHEEYKWLEKNTRPL 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ApepP	NP_001246053.1	Creatinase_N	9..154	CDD:307473	54/144 (38%)
		Creatinase_N_2	158..318	CDD:318430	50/176 (28%)
		APP	321..545	CDD:238518	110/223 (49%)
		Peptidase_M24_C	551..613	CDD:318429	14/61 (23%)
xpnpep2	XP_031747549.1	Creatinase_N	83..202	CDD:396058	48/126 (38%)
		Creatinase_N_2	222..387	CDD:406573	50/175 (29%)
		APP	391..610	CDD:238518	110/223 (49%)
		Peptidase_M24_C	613..677	CDD:406572	14/63 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62675
OrthoDB	1	1.010	-	-		D265764at33208
OrthoFinder	1	1.000	-	-		FOG0001510
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43763
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1687
SonicParanoid	1	1.000	-	-		X1075
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060