DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12288 and HNRNPDL

DIOPT Version :10

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_112740.1	Gene:	HNRNPDL / 9987	HGNCID:	5037	Length:	420	Species:	Homo sapiens

Alignment Length:	41	Identity:	14/41 - (34%)
Similarity:	18/41 - (43%)	Gaps:	11/41 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LEYRLPLEF-IQKKVLHVTIWSHDSLQENAFLGGIELPLAE 43
            |.|.||..| |.||.|  ::.:.:.|        |..||.|
Human   917 LRYFLPPSFPISKKEL--SVMNSEEL--------ISFPLKE 947

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	156..237	CDD:409828
CG12288	NP_609822.1	RRM_SF	261..332	CDD:473069
HNRNPDL	NP_112740.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..83
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	96..120
		RRM1_hnRPDL	149..224	CDD:410152
		RRM2_hnRPDL	234..308	CDD:409998
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	313..348
		Necessary for interaction with TNPO1. /evidence=ECO:0000269\|PubMed:9524220	342..420
		Necessary for its nuclear import and export	396..420
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	398..420
Blue background indicates that the domain is not in the aligned region.

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