Protein Alignment CG12288 and NAM8

DIOPT Version :10

• Sequence 1: NP_609822.1
• Gene: CG12288 / 35027
• FlyBaseID: FBgn0032620
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: NP_011954.1
• Gene: NAM8 / 856486
• SGDID: S000001128
• Length: 523
• Species: Saccharomyces cerevisiae
• Alignment Length: 240
• Identity: 59/240 - (24%)
• Similarity: 91/240 - (37%)
• Gaps: 71/240 - (29%)

  Fly   120 PNEKPKGKVSKKAKANANNKDEEGVKRIRNPAEEASTVFVGNLPINTKRVQLVKLF--------- 175
            ||:|.|...:..:.:|:|| ....||...|     .::|||:|..|....||.:||
Yeast   134 PNKKLKLNWATSSYSNSNN-SLNNVKSGNN-----CSIFVGDLAPNVTESQLFELFINRYASTSH 192

  Fly   176 ------------QPYGLV----------------------QSIRLRTAGGKQLF---KHKQRKVA 203
                        :.||.|                      ::|::....|:|..   .:...:.:
Yeast   193 AKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSS 257

  Fly   204 GSLNAYVVLEKPEIAQQALALNGSE---FKENHLRVTPASMAEKFGQAKDKQPS-----DKDAKR 260
            .|||...|..:.....|:...||:.   ||.||:        .:|.....:|||     |.: ..
Yeast   258 SSLNNENVDSRFLSKGQSFLSNGNNNMGFKRNHM--------SQFIYPVQQQPSLNHFTDPN-NT 313

  Fly   261 TIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDGDKGCKGVAYV 305
            |:|:|.|....||::||..|...|.|.|:: :..| |.|..|.||
Yeast   314 TVFIGGLSSLVTEDELRAYFQPFGTIVYVK-IPVG-KCCGFVQYV 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	156..237	CDD:409828	26/129 (20%)
		RRM_SF	261..332	CDD:473069	18/45 (40%)
NAM8	NP_011954.1	RRM1_NGR1_NAM8_like	55..144	CDD:410023	4/9 (44%)
		RRM2_SECp43_like	162..241	CDD:409781	14/83 (17%)
		RRM3_NGR1_NAM8_like	312..383	CDD:409782	18/47 (38%)