DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12288 and MIP6

DIOPT Version :9

Sequence 1:NP_609822.1 Gene:CG12288 / 35027 FlyBaseID:FBgn0032620 Length:435 Species:Drosophila melanogaster
Sequence 2:NP_011879.1 Gene:MIP6 / 856408 SGDID:S000001057 Length:659 Species:Saccharomyces cerevisiae


Alignment Length:454 Identity:87/454 - (19%)
Similarity:148/454 - (32%) Gaps:173/454 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 VTKKSKTKPKKKTVKVPKDEVKAAVQESPKKLSAKDLAKIEKKKAKKQAQKLK----KQQNKLAP 89
            ::..||..|:..:...|.|  |.|.|:|.|.:||:.|.:::....|....|||    |::|.|..
Yeast    12 ISLNSKQNPRSISKSCPND--KDARQKSFKTISAQALVRVQGAGYKLGDVKLKDAEVKEKNSLKK 74

  Fly    90 KEIKT---EPEAQVKVESKATKKEKVEKEPTTAPNEKPKGKVSKKAKANANNKDEEGVKRIRNPA 151
            .:.|.   |.:.|.:|..|...|..|:|            .::|.:|.|                
Yeast    75 YDCKNATQEKKEQEQVFEKTVAKGSVQK------------YITKTSKTN---------------- 111

  Fly   152 EEASTVFVGNLPINTKRVQLVKLFQPYGLVQSIRL-------RTAG-GKQLFKHKQ--------- 199
                ::|:|||........|.|:|:.|...:|.::       ::.| |...||.|.         
Yeast   112 ----SLFIGNLKSTVTEEMLRKIFKRYQSFESAKVCRDFLTKKSLGYGYLNFKDKNDAESARKEF 172

  Fly   200 ---------------------RKVAGSLNAY---VVLEKPEIAQQALAL---------------- 224
                                 ||..|: |.:   :.||.|::..::..|                
Yeast   173 NYTVFFGQEVKIMPSMKNTLFRKNIGT-NVFFSNLPLENPQLTTRSFYLIMIEYGNVLSCLLERR 236

  Fly   225 ---------------------NGSEFKEN----------HLRVTPASMAEKFGQAKD-------- 250
                                 |..||..|          .:|..|.....|.....|        
Yeast   237 KNIGFVYFDNDISARNVIKKYNNQEFFGNKIICGLHFDKEVRTRPEFTKRKKMIGSDIVIEDELL 301

  Fly   251 --KQPSDKDAKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDGDKGCKGVAYVCFQKPDAV 313
              ...||....:||.|.:|....|:|::.:.||:.|.|..: .:.:........|:|.::..:..
Yeast   302 ASNNLSDNARSKTILVKNLPSDTTQEEVLDYFSTIGPIKSV-FISEKQANTPHKAFVTYKNEEES 365

  Fly   314 GLALE-LNQTLL----------DDRPINVERYQVKKLGAKQVRDAAAASAASKTSSKTKAKNQN 366
            ..|.: ||:|:.          .|:|::      .::|               |:.|||...:|
Yeast   366 KKAQKCLNKTIFKNHTIWVGPGKDKPVH------NQIG---------------TNKKTKVYLKN 408

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12288NP_609822.1 RRM1_RBM34 155..237 CDD:240840 27/169 (16%)
RRM_SF 261..332 CDD:302621 18/81 (22%)
MIP6NP_011879.1 RRM 8..>187 CDD:223796 45/208 (22%)
RRM1_PES4_MIP6 111..190 CDD:410180 15/98 (15%)
RRM2_PES4_MIP6 200..275 CDD:410181 9/74 (12%)
RRM3_PES4_MIP6 313..385 CDD:410182 16/72 (22%)
RRM4_PES4_MIP6 400..478 CDD:410183 4/9 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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