Protein Alignment CG12288 and TIF3

DIOPT Version :10

• Sequence 1: NP_609822.1
• Gene: CG12288 / 35027
• FlyBaseID: FBgn0032620
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: NP_015489.1
• Gene: TIF3 / 856292
• SGDID: S000006367
• Length: 436
• Species: Saccharomyces cerevisiae
• Alignment Length: 405
• Identity: 81/405 - (20%)
• Similarity: 134/405 - (33%)
• Gaps: 135/405 - (33%)

  Fly   109 KEKVEKEPTTAP------NEKPKGKVSKKAKANANNKDEEGV--------------------KRI 147
            :|.|:....|.|      |..|..::: .||.|:||....|.                    :|.
Yeast    28 EEDVDLNKITIPIETANANTIPLSELA-HAKNNSNNTRSGGFGGSFGGRSRLDPALGGGSSDRRE 91

  Fly   148 RNPAEEAS--TVFVGNLP--INTKRVQ------LVK------LFQPYGLVQSIRLRTAGGKQLFK 196
            ..|..:|.  ...:.|:|  |..:.||      |||      :..|..|....||:   |.....
Yeast    92 EYPVPDAPPYRAVINNIPWDITPEGVQAWVEDGLVKPEAVEEVVLPKNLRDPTRLK---GNAFVT 153

  Fly   197 HKQR-------KVAGS-LN---AYVVLEKPEIAQQA----LALNGSEFKENHLRVTP-----ASM 241
            .|:|       |..|: ||   .||.:..|.....|    .:..||.|:.:.....|     |:.
Yeast   154 LKERADLVAVLKFNGTKLNERTVYVSVAAPRRGGGADVDWSSARGSNFQGDGREDAPDLDWGAAR 218

  Fly   242 AEKF-GQAKDKQPSDKD---AKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDGDKGCKGV 302
            ...| |..::::..|.|   |:.:.|.||.:....|.:  |:     :||:........:|
Yeast   219 GSNFRGPRREREEVDIDWTAARGSNFQGSSRPPRRERE--EV-----DIDWSAARGSNFQG---- 272

  Fly   303 AYVCFQKPDAVGLALELNQTLLDDRPINVERYQVKKLGAKQVRDAAAASAASKTSSK-------- 359
                                  ..||...||.:      ..:..:||..:..::||:
Yeast   273 ----------------------SSRPPRREREE------PDIDWSAARGSNFQSSSRPPRREREE 309

  Fly   360 -----TKAKNQNSAGAKKRLDKKKGKENGSL---KKEGAPTG--QKKKSEYRGVKVDGIKKAKKP 414
                 :.|:..|...:.:...:::.||..:|   ...||..|  |:.|:.|        |.....
Yeast   310 PDIDWSAARGSNFQSSSRPPRREREKEEPALDWGAARGAQFGKPQQTKNTY--------KDRSLT 366

  Fly   415 KKKSNDQQTALAKKI 429
            .||:.|:|..:.|.:
Yeast   367 NKKTTDEQPKIQKSV 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	156..237	CDD:409828	26/109 (24%)
		RRM_SF	261..332	CDD:473069	10/70 (14%)
TIF3	NP_015489.1	RRM4_RBM12_like	102..179	CDD:409936	20/79 (25%)