DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and tia1

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_997793.1	Gene:	tia1 / 793165	ZFINID:	ZDB-GENE-030131-1506	Length:	386	Species:	Danio rerio

Alignment Length:	235	Identity:	57/235 - (24%)
Similarity:	91/235 - (38%)	Gaps:	58/235 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 EEASTVFVGNLPINTKRVQLVKLFQPYGLVQSIRL--RTAGGK-----QLFKHKQRKVAGSLNAY 209
            |:..|::||||..:.....:::||...|..:|.::  .|||..     :.|:|  |..|.||
Zfish     5 EQPKTLYVGNLSRDVTEALIMQLFGQIGPCKSCKMIVDTAGNDPYCFVEFFEH--RHAAASL--- 64

  Fly   210 VVLEKPEIAQQALALNGSEFKENHLRVTPASMAEKFGQAKDKQPSDKDAKRTIFVGSLKYSATEE 274
                        .|:||.:.....::|..|:       :...|..|......:|||.|....|.:
Zfish    65 ------------AAMNGRKIMGKEVKVNWAT-------SPSSQKKDTSNHFHVFVGDLSPEITTD 110

  Fly   275 QLREIFSSCGEIDYIRCLQDGDKG-CKGVAYVC-FQKPDAVGLALELNQTLLDDRPINVERYQVK 337
            .:|..|:..|.|...|.::|...| .||..:|. |.|.||...               :::...:
Zfish   111 DIRAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENA---------------IQQMGGQ 160

  Fly   338 KLGAKQVRD--AAAASAASKTSSKTKAK--------NQNS 367
            .||.:|:|.  |.....|.|.:.:|..|        ||:|
Zfish   161 WLGGRQIRTNWATRKPPAPKATYETNTKHLSFDEVVNQSS 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	21/88 (24%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	19/72 (26%)
tia1	NP_997793.1	ELAV_HUD_SF	6..270	CDD:273741	56/234 (24%)
		RRM1_TIA1	9..82	CDD:241059	22/89 (25%)
		RRM2_TIA1	95..174	CDD:241062	24/93 (26%)
		RRM3_TIA1	204..277	CDD:241065
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910