DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and pspc1

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001038723.1	Gene:	pspc1 / 692285	ZFINID:	ZDB-GENE-030131-9530	Length:	512	Species:	Danio rerio

Alignment Length:	373	Identity:	81/373 - (21%)
Similarity:	155/373 - (41%)	Gaps:	84/373 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 QVKVESKAT--KKEKVEKEPTTAPNEKPKGKV-----SKKAKANANNKDEE---GVKRIRNPAEE 153
            ||.:::.||  .::.|.:. |.:|.: ||..:     |.:..::||::.:|   .:|..|.|.|:
Zfish     8 QVNIQNNATFPHQQNVTRS-TESPGD-PKETMEAVAPSPQDPSSANSEPQEMTVDIKNFRRPGEK 70

  Fly   154 AST----VFVGNLPINTKRVQLVKLFQPYGLVQSIRLRTAGGKQLFKHKQRKVAGSLNAYVVLEK 214
            ..|    :||||||.:.......|||..||          ..|::|.::.|..     .::.||.
Zfish    71 TFTQRCRLFVGNLPSDMADEDFKKLFFKYG----------DAKEVFINRDRGF-----GFIRLET 120

  Fly   215 PEIAQQALA-LNGSEFKENHLRVTPASMAEKFGQAKDKQPSDKDAKRTIFVGSLKYSATEEQLRE 278
            ..:|:.|.| |:|:......:|:..|:    .|.|             :.|.:|....:.|.|.:
Zfish   121 RTLAEIAKAELDGTVLGNRPIRIRFAT----HGAA-------------LTVRNLSPVVSNELLEQ 168

  Fly   279 IFSSCGEIDYIRCLQDGDKG---CKGVAYVCFQKPDAVGLALE--LNQTLL---DDRPI---NVE 332
            .||..|.::....:.| |:|   .||:  |.|....|...||:  .:..||   ..||:   ..|
Zfish   169 AFSQFGPVERAIVIVD-DRGRPTGKGI--VEFANKPAARKALDHCADGALLLTTSPRPVILEPTE 230

  Fly   333 RY---------------QVKKLGAKQVRDAAAASAASKTSSKTKAKNQNSAGAKKRLDK--KKGK 380
            :|               |..|....:...|...:...:.||:.||.::.....::::::  ::.|
Zfish   231 QYDDEDGLPEKLLQKSAQYHKEREHKPHFAQPGTFEFEYSSRWKALDEMDKQQREQVERNIQEAK 295

  Fly   381 ENGSLKKEGAPTGQKKKSEYRGVKVDGIKKAKKPKKKSNDQQTALAKK 428
            |....:.|.|    |::.:...::.|.:::.::.::....:...|.|:
Zfish   296 EKLETEMEAA----KQEHQLMMMRQDLMRRQEELRRLEELRNQELQKR 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	23/86 (27%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	21/81 (26%)
pspc1	NP_001038723.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..56		12/49 (24%)
		RRM1_PSP1	75..145	CDD:241030	22/84 (26%)
		RRM2_PSP1	151..230	CDD:241033	22/94 (23%)
		NOPS_PSPC1	221..314	CDD:240584	16/96 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	451..512
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910