DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and RBM3

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_006734.1	Gene:	RBM3 / 5935	HGNCID:	9900	Length:	157	Species:	Homo sapiens

Alignment Length:	151	Identity:	34/151 - (22%)
Similarity:	63/151 - (41%)	Gaps:	17/151 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   254 SDKDAKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDGD-KGCKGVAYVCFQKPDAVGLAL 317
            |.::.|  :|||.|.::..|:.|.:.|||.|.|..:..::|.: :..:|..::.|..|:...:|:
Human     2 SSEEGK--LFVGGLNFNTDEQALEDHFSSFGPISEVVVVKDRETQRSRGFGFITFTNPEHASVAM 64

  Fly   318 E-LNQTLLDDRPINVERYQVKKLGAKQVRDAAAASAASKTSSKTKAKNQNSAGAKKRLDKKKGKE 381
            . :|...||.|.|.|:.......|.:    .....|..:..|.::.......|:.:..|.:.|
Human    65 RAMNGESLDGRQIRVDHAGKSARGTR----GGGFGAHGRGRSYSRGGGDQGYGSGRYYDSRPG-- 123

  Fly   382 NGSLKKEGAPTGQKKKSEYRG 402
                   |...|..:..:|.|
Human   124 -------GYGYGYGRSRDYNG 137

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	21/72 (29%)
RBM3	NP_006734.1	RRM_CIRBP_RBM3	6..85	CDD:409883	23/80 (29%)
RBM3	NP_006734.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	81..157		10/70 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910