DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and hnrnpd

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001103930.1	Gene:	hnrnpd / 560522	ZFINID:	ZDB-GENE-070424-97	Length:	314	Species:	Danio rerio

Alignment Length:	280	Identity:	64/280 - (22%)
Similarity:	107/280 - (38%)	Gaps:	67/280 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 TKKEKVEKEPTTAPNEKPKGK---VSKKAKANANNKDEEGVK--RIRNPAEEASTVFVGNLPINT 166
            ::::.:.::||....|...|:   ..:.:..|....:.||.|  ..:|..:|.. :|||.|..:|
Zfish     2 SEEQFLGEDPTMKMEENDDGEGFGEEQMSGDNGGQGEAEGSKIDASKNEEDEGK-MFVGGLSWDT 65

  Fly   167 KRVQLVKLFQPYGLVQSIRL-------RTAG-GKQLFKHKQRKVAGSLNAYVVLEKPEIAQQALA 223
            .:..|...|..:|.|....|       |:.| |..|||..:.           :|| .|.|:...
Zfish    66 TKKDLKDYFTKFGEVVDCTLKLDPLTGRSRGFGFVLFKEAES-----------VEK-VITQKEHK 118

  Fly   224 LNGSEFKENHLRVTPASMAEKFGQAKDKQPSDKDAKRTIFVGSLKYSATEEQLREIFSSCGEIDY 288
            |||..       :.|    :|....|.|:|..|     ||||.|.....||::||.|.:.||::.
Zfish   119 LNGKV-------IDP----KKAKAMKTKEPVKK-----IFVGGLSPDTPEEKIREYFDAYGEVES 167

  Fly   289 IRC-LQDGDKGCKGVAYVCFQKPDAVGLALELNQTLLDDRPINVERYQVKKLGAKQVRDAAAASA 352
            |.. :::.....:|..::.|:                       |...|||:..|...:...:..
Zfish   168 IELPMENKTNKRRGFCFITFK-----------------------EEEPVKKIMEKMYHNIGLSKC 209

  Fly   353 ASKTS-SKTKAKNQNSAGAK 371
            ..|.: ||.:.:.|...|.:
Zfish   210 EVKVAMSKEQYQQQQQWGGR 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	23/89 (26%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	15/71 (21%)
hnrnpd	NP_001103930.1	CBFNT	3..54	CDD:285369	9/50 (18%)
		RRM1_hnRNPD_like	56..129	CDD:241019	24/95 (25%)
		RRM2_hnRNPD	140..214	CDD:241027	22/101 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910