DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and celf1

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	XP_012816629.1	Gene:	celf1 / 549906	XenbaseID:	XB-GENE-854036	Length:	534	Species:	Xenopus tropicalis

Alignment Length:	273	Identity:	63/273 - (23%)
Similarity:	102/273 - (37%)	Gaps:	68/273 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 NEKPKGKVSKKAKANANNKDEEGVKRIRNPAEEASTVFVGNLPINTKRVQLVKLFQPYGLVQSI- 184
            |..|   ||||.....::.|        :|..::..:|||.:|.:....:|.:||:.||.|..|
Frog    20 NSSP---VSKKMNGTMDHPD--------HPDPDSIKMFVGQVPRSWSEKELRELFEQYGAVYEIN 73

  Fly   185 --RLRTAGGKQ-----LFKHKQRKVAGSLNAYVVLEKPEIAQQAL----ALNGSEFKENHLRVTP 238
              |.|:....|     ......||.|        ||    ||.||    .|.|   ..:.:::.|
Frog    74 VLRDRSQNPPQSKGCCFITFYTRKAA--------LE----AQNALHNMKVLPG---MHHPIQMKP 123

  Fly   239 ASMAEKFGQAK----DKQPSDKDAKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDGDKGC 299
            |...:..|...    .:.|:..: .|.:|||.:.....|..:|.:||..|:|:..|.|:..|...
Frog   124 ADSEKNNGGLNTVLYPEHPASVE-DRKLFVGMVSKKCNENDIRAMFSQFGQIEESRILRGPDGMS 187

  Fly   300 KGVAYVCFQKPDAVGLALELNQTLLDDRPINVERYQVKKLGAKQVRDAAAASAASKTSSKTKAKN 364
            :|.|:|.|.......:|                   :|.:...|..:..::....|.:...|.|.
Frog   188 RGCAFVTFTTRSMAQMA-------------------IKAMHQAQTMEGCSSPIVVKFADTQKDKE 233

  Fly   365 QNSAGAKKRLDKK 377
            |      ||:.::
Frog   234 Q------KRMTQQ 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	25/93 (27%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	17/70 (24%)
celf1	XP_012816629.1	RRM1_CELF1_2_Bruno	42..125	CDD:241075	26/97 (27%)
		ELAV_HUD_SF	45..529	CDD:273741	55/237 (23%)
		RRM2_CELF1_2	147..227	CDD:241078	21/98 (21%)
		RRM3_CELF1_2	442..533	CDD:241082
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910