Protein Alignment CG12288 and Hnrnpa2b1

DIOPT Version :10

• Sequence 1: NP_609822.1
• Gene: CG12288 / 35027
• FlyBaseID: FBgn0032620
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: NP_001361674.1
• Gene: Hnrnpa2b1 / 53379
• MGIID: 104819
• Length: 353
• Species: Mus musculus
• Alignment Length: 260
• Identity: 54/260 - (20%)
• Similarity: 92/260 - (35%)
• Gaps: 73/260 - (28%)

  Fly   112 VEKEPTTAPNEKPKGKVSKKAKANANNKDEEGVKRIRNPAEEASTVFVGNLPINTKRVQLVKLFQ 176
            :||...|.|.|:.|             :::|..:::          |:|.|...|....|...::
Mouse     1 MEKTLETVPLERKK-------------REKEQFRKL----------FIGGLSFETTEESLRNYYE 42

  Fly   177 PYG-LVQSIRLRTAGGKQ-------LFKHKQRKVAG------SLNAYVVLEKPEIAQQALALNGS 227
            .:| |...:.:|....|:       .|.......|.      |::..||..|..:|::.....|:
Mouse    43 QWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGA 107

  Fly   228 EFKENHLRVTPASMAEKFGQAKDKQPSDKDAKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCL 292
                 |:.|                       :.:|||.:|....|..||:.|...|:||.|..:
Mouse   108 -----HVTV-----------------------KKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEII 144

  Fly   293 QDGDKGCK-GVAYVCFQKPDAVG-LALELNQTLLDDRPINVERYQVKKLGAKQVRDAAAASAASK 355
            .|...|.| |..:|.|...|.|. :.|:...|      ||....:|:|..::|......:|.:.:
Mouse   145 TDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHT------INGHNAEVRKALSRQEMQEVQSSRSGR 203

  Fly   356  355
            Mouse   204  203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	156..237	CDD:409828	18/94 (19%)
		RRM_SF	261..332	CDD:473069	24/72 (33%)
Hnrnpa2b1	NP_001361674.1	Nuclear localization signal. /evidence=ECO:0000255	9..15		3/18 (17%)
		RRM1_hnRNPA2B1	19..99	CDD:410155	15/89 (17%)
		RRM2_hnRNPA2B1	112..191	CDD:409995	26/84 (31%)
		Disordered. /evidence=ECO:0000250|UniProtKB:P22626	193..353		1/11 (9%)
		HnRNPA1	302..326	CDD:463312
		Nuclear targeting sequence. /evidence=ECO:0000250	308..347