DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and hnrnpabb

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_998467.1	Gene:	hnrnpabb / 406594	ZFINID:	ZDB-GENE-040426-2516	Length:	309	Species:	Danio rerio

Alignment Length:	282	Identity:	69/282 - (24%)
Similarity:	102/282 - (36%)	Gaps:	77/282 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 KANANNKDEEGVKRIRNPAEE-ASTVFVGNLPINTKRVQLVKLFQPYGLVQ--SIRLRTAGGKQ- 193
            :|...|...||::...:..|| |..:|||.|..:|.:..|...|..:|.|.  :|::.:..|:.
Zfish    22 EAAGENGAGEGLQIDASKCEEDAGKMFVGGLSWDTSKKDLKDYFSKFGEVMDCTIKMDSNTGRSR 86

  Fly   194 -----LFKHKQRKVAGSLNAYVVLEKPEIAQQALALNGSEFKENHL---RVTPASMAEKFGQAKD 250
                 |||...             ....:.||         ||:.|   ::.|     |...|..
Zfish    87 GFGFILFKESD-------------SVDRVLQQ---------KEHRLDGRQIDP-----KRAMAIK 124

  Fly   251 KQPSDKDAKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDGDKGCK--GVAYVCFQKPDAV 313
            |:|..|     ||||.|....|||::||.|.|.|||:.|. |....|..|  |..::.|:
Zfish   125 KEPVKK-----IFVGGLNPETTEEKIREYFGSFGEIETIE-LPTDPKTSKRRGFVFITFK----- 178

  Fly   314 GLALELNQTLLDDRPINVERYQVKKLGAKQVRDAAAASAASKTSSKTKAKNQNSAGAKKRLDKKK 378
                              |.:.|||:..|:..:...:....|.:...:...|...||      :.
Zfish   179 ------------------EEFAVKKILEKKYHNVCGSKCEIKIAQPKEIYQQQQFGA------RG 219

  Fly   379 GKENGSLKKEGAPTGQKKKSEY 400
            |...|..:..|.| ||.....|
Zfish   220 GGFGGRGRGRGGP-GQSWNQGY 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	19/92 (21%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	21/72 (29%)
hnrnpabb	NP_998467.1	CBFNT	2..45	CDD:285369	6/22 (27%)
		RRM1_hnRNPAB	46..120	CDD:241201	21/100 (21%)
		RRM_SF	125..204	CDD:302621	30/107 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910