DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and cocoon

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001261874.1	Gene:	cocoon / 39665	FlyBaseID:	FBgn0036496	Length:	318	Species:	Drosophila melanogaster

Alignment Length:	190	Identity:	44/190 - (23%)
Similarity:	66/190 - (34%)	Gaps:	56/190 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 DEEGVKRIRNPAEEASTVFVGNLP-------------INTKRVQLVKLFQPYGLVQSIRLRTAGG 191
            ::||.:.|..||||..|:.:..|.             ::||.|:.|              |:..|
  Fly     8 EKEGDEPIELPAEEDGTLLLSTLQAQFPESSGLQYRNVDTKAVRGV--------------RSNEG 58

  Fly   192 KQLFKHKQRKVAGSLNAYVVLEKPEIAQQALALNGSEFK----ENHLRVTPASMAEKFGQAKDKQ 252
            : |:...:....|..:.:.|..|....|....|..|..|    |.|||..
  Fly    59 R-LYSPSEETGWGEYHYFCVFPKKNKRQSEDNLENSTAKTKRTEAHLRCF--------------- 107

  Fly   253 PSDKDAKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDGDKG-CKGVAYVCFQKPD 311
                    .:.|..|.|:.||:.|||.|.:.|::......:|...| .||..:|.|...|
  Fly   108 --------DLIVLGLSYNTTEQDLREYFETYGDVVKAEIKKDTRSGHSKGFGFVRFGSYD 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	20/98 (20%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	17/52 (33%)
cocoon	NP_001261874.1	RRM1_TDP43	108..184	CDD:240767	17/52 (33%)
cocoon	NP_001261874.1	RRM2_TDP43	193..262	CDD:240768
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910