DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and tial1

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	XP_005156854.1	Gene:	tial1 / 394107	ZFINID:	ZDB-GENE-040426-1547	Length:	399	Species:	Danio rerio

Alignment Length:	224	Identity:	52/224 - (23%)
Similarity:	82/224 - (36%)	Gaps:	46/224 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 TVFVGNLPINTKRVQLVKLFQPYGLVQSIRLRTAGGKQLFKHKQRKVAGSLNAYVVL-------- 212
            |::||||..:.....:::||...|..:|.::.|..     ....||:..|...:.||
Zfish     9 TLYVGNLSRDVTENLILQLFTQIGPCKSCKMITEQ-----SDSSRKMNSSSIGFSVLQHTSNDPY 68

  Fly   213 ------EKPEIAQQALALNGSEFKENHLRV----TPASMAEKFGQAKDKQPSDKDAKRTIFVGSL 267
                  |..:.|....|:||.:.....::|    ||:|           |..|......:|||.|
Zfish    69 CFVEFFEHRDAAAALAAMNGRKILGKEVKVNWATTPSS-----------QKKDTSNHFHVFVGDL 122

  Fly   268 KYSATEEQLREIFSSCGEIDYIRCLQDGDKG-CKGVAYVCF-----------QKPDAVGLALELN 320
            ....|.:.:|..|:..|:|...|.::|...| .||..:|.|           :..||....:.:.
Zfish   123 SPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLVRLQYRNRVKDAENAIVHMG 187

  Fly   321 QTLLDDRPINVERYQVKKLGAKQVRDAAA 349
            ...|..|.|.......|....|.|:|.:|
Zfish   188 GQWLGGRQIRTNWATRKPPAPKSVQDNSA 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	21/98 (21%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	21/82 (26%)
tial1	XP_005156854.1	RRM	7..295	CDD:223796	52/224 (23%)
		RRM_SF	9..108	CDD:302621	24/114 (21%)
		RRM2_TIAR	114..203	CDD:241061	21/88 (24%)
		RRM3_TIAR	233..305	CDD:241064
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910