DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and pabpc1b

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_957176.1	Gene:	pabpc1b / 393856	ZFINID:	ZDB-GENE-050308-1	Length:	634	Species:	Danio rerio

Alignment Length:	337	Identity:	82/337 - (24%)
Similarity:	135/337 - (40%)	Gaps:	95/337 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 PAEEASTVFVGNLPINTKRVQLVKLFQPYGLVQSIRL-------RTAGGKQLFKHKQRKVAGSLN 207
            |:...::::||:|..:.....|.:.|.|.|.:.|||:       |:.|                .
Zfish     6 PSYPMASLYVGDLHQDVTEAMLYEKFSPAGAILSIRVCRDMITRRSLG----------------Y 54

  Fly   208 AYVVLEKPEIAQQAL-ALNGSEFKENHLRVTPASMAEKFGQAKDKQPS-DKDAKRTIFVGSLKYS 270
            |||..::|..|::|| .:|....|...:|:          ....:.|| .|.....||:.:|..|
Zfish    55 AYVNFQQPADAERALDTMNFDVIKGRPVRI----------MWSQRDPSLRKSGVGNIFIKNLDKS 109

  Fly   271 ATEEQLREIFSSCGEIDYIRCLQDGDKGCKGVAYVCFQKPDAVGLALE-LNQTLLDDRPINVERY 334
            ...:.|.:.||:.|.|...:.:.| :.|.||..:|.|:..:|...|:| :|..||:||.:.|.|:
Zfish   110 IDNKALYDTFSAFGNILSCKVVCD-ENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRF 173

  Fly   335 QVKK-----LGAK-------------------QVRD-----AAAASAASKTSSKTKAKN------ 364
            :.:|     |||:                   :::|     ..|.|....|....|::.
Zfish   174 KSRKEREAELGARAKEFTNVYIKNFGEDMDDDKLKDIFSKYGNAMSIRVMTDENGKSRGFGFVSF 238

  Fly   365 QNSAGAKKRLDKKKGKE-NGSL-------KKEGAPTGQKKKSE---------YRGVKV------D 406
            :....|::.:|:..||| ||.|       ||....|..|:|.|         |:||.:      |
Zfish   239 ERHEDAQRAVDEMNGKEMNGKLIYVGRAQKKVERQTELKRKFEQMKQDRMTRYQGVNLYVKNLDD 303

  Fly   407 GIKKAKKPKKKS 418
            ||...:..|:.|
Zfish   304 GIDDERLRKEFS 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	22/89 (25%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	23/71 (32%)
pabpc1b	NP_957176.1	PABP-1234	11..613	CDD:130689	81/332 (24%)
		RRM1_I_PABPs	12..91	CDD:240824	22/104 (21%)
		RRM2_I_PABPs	97..172	CDD:240825	24/75 (32%)
		RRM3_I_PABPs	190..269	CDD:240826	13/78 (17%)
		RRM4_I_PABPs	293..370	CDD:240827	7/23 (30%)
		PABP	545..612	CDD:279051
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910