DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and hnrnpa1a

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	XP_021335234.1	Gene:	hnrnpa1a / 393467	ZFINID:	ZDB-GENE-040426-1546	Length:	445	Species:	Danio rerio

Alignment Length:	274	Identity:	57/274 - (20%)
Similarity:	108/274 - (39%)	Gaps:	40/274 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 PTTAPNEKPKGKVSKKAKANANNKDEEGVKRIRNPAEEASTVFVGNLPINTKRVQLVKLFQPYGL 180
            |...|.::.:.:.:...:..|.:|:::   ..|.| |:...:|:|.|...|....|...|:.:|.
Zfish     3 PAITPKKEREAESAVSHRVTAMSKEQQ---TPREP-EQLRKLFIGGLSFETTDESLRAHFEQWGT 63

  Fly   181 VQSIRLRTAGGKQLFKHKQR---KVAGSLNAYVVLEKP--------------EIAQQALALNGSE 228
            :....:..:....:..:::.   ||||.|....|:..|              .:.:...|::...
Zfish    64 LTDCVVSPSAAIHMLMYEREEHLKVAGFLYCSQVMRDPNTKRSRGFGFVTYSSVGEVDAAMDARP 128

  Fly   229 FKENHLRVTPASMAEKFGQAKDKQPSDKDAKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCL- 292
            .|.:...|.|.....:...:|   |......:.:|||.:|....||.|||.|...|:||.:..:
Zfish   129 HKVDGRAVEPKRAVSREDSSK---PGAHSTVKKMFVGGIKEDTDEEHLREYFGQFGKIDEVNIMT 190

  Fly   293 -QDGDKGCKGVAYVCFQKPDAVGLALELNQTLLDDRPINVERYQVKKLGAKQVRDAAAASAASKT 356
             ::.||. :|.|::.|...|||            || |.:::|........:||.|.:....::.
Zfish   191 EKNSDKR-RGFAFITFDDHDAV------------DR-IVIQKYHTVNGHNCEVRKALSREEMNRV 241

  Fly   357 SSKTKAKNQNSAGA 370
            |..::.......|:
Zfish   242 SMNSRGGRGGGGGS 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	16/98 (16%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	24/72 (33%)
hnrnpa1a	XP_021335234.1	RRM_SF	36..144	CDD:327398	18/107 (17%)
		RRM_SF	157..233	CDD:327398	27/89 (30%)
		HnRNPA1	376..>392	CDD:314495
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910