Protein Alignment CG12288 and PABPN1L

DIOPT Version :10

• Sequence 1: NP_609822.1
• Gene: CG12288 / 35027
• FlyBaseID: FBgn0032620
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: NP_001372638.1
• Gene: PABPN1L / 390748
• HGNCID: 37237
• Length: 297
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 66/333 - (19%)
• Similarity: 107/333 - (32%)
• Gaps: 89/333 - (26%)

  Fly    92 IKTEPEAQVKVESKATKKEKVEKEPTTAPNEKPKGKVSKKAKANANNKDEEG-------VKRIRN 149
            :.::||||.......||:       ...| |..:||..|:.:.:| .:|::|       :....|
Human    21 VSSDPEAQGWGAWNETKE-------ILGP-EGGEGKEEKEEEEDA-EEDQDGDAGFLLSLLEQEN 76

  Fly   150 PAEEASTVFVGNLPINTKRVQLVKLFQPYGLVQSIRLRTAGGKQLFKHKQRKVAGSLNAYVVLEK 214
            .||         .|:..:.::.:|:                          ||.....|......
Human    77 LAE---------CPLPDQELEAIKM--------------------------KVCAMEQAEGTPRP 106

  Fly   215 PEIAQQALALNGSEFKENHLRVTPASM-AEKFGQAKDKQPSDKDAKRTIFVGSLKYSATEEQLRE 278
            |.:.|||....|:...:   .::|.:: ....|..::|..:|   .|:::||:|       .|..
Human   107 PGVQQQAEEEEGTAAGQ---LLSPETVGCPLSGTPEEKVEAD---HRSVYVGNL-------CLHR 158

  Fly   279 IFSSCGEIDYIRCLQDGDKGCKGVAYVCFQKPDAVGLALELNQTLLDD-----RPINVERYQVKK 338
            :           |.|....|.:|........|...| |.|.||...|.     .|....|.|...
Human   159 V-----------CHQGLRAGRRGAGPEPLPGPGHQG-AAEKNQLPWDQLHRPRGPSRTPRLQGGT 211

  Fly   339 LGAKQVRDAAAASAASKTSSKTKAKNQNSAGAKKRLDKKKGKENGSLKK-------EGAPTGQKK 396
            |..::....|.|..........|.........|.|.|.::|.......|       .||.:|...
Human   212 LPPQRPPGQAPAQTTRAEPGPWKILTMVFTVLKGRPDFERGAGAWIRSKPLVLHPGAGAGSGAGA 276

  Fly   397 KSEYRGVK 404
            :.|.|||:
Human   277 RPEERGVQ 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	156..237	CDD:409828	10/80 (13%)
		RRM_SF	261..332	CDD:473069	16/75 (21%)
PABPN1L	NP_001372638.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..66		14/53 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..128		5/29 (17%)