DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12288 and hnrnpa0b

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_999871.1	Gene:	hnrnpa0b / 334222	ZFINID:	ZDB-GENE-030131-6154	Length:	314	Species:	Danio rerio

Alignment Length:	227	Identity:	60/227 - (26%)
Similarity:	90/227 - (39%)	Gaps:	34/227 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 EEASTVFVGNLPINTKRVQLVKLFQPYG------LVQSIRLRTAGGKQLFKHKQRKVAGSLNAYV 210
            |:...:|||.|.:.|....|...|:.:|      :||:.:|:.:   :.|            .:|
Zfish     5 EKLCKLFVGGLNVQTTNDGLRSYFEQFGNLTDCVVVQNDQLQRS---RCF------------GFV 54

  Fly   211 VLEKPEIAQQALALNGSEFKENHLRVTPASMAEKFGQAKDKQPSDKDAKRTIFVGSLKYSATEEQ 275
            .....|.|..|:|.........::.|..|...|..|     :|......:.||||.||....|:.
Zfish    55 TYSTSEEADAAMAARPHVVDGKNVEVKRAVAREDAG-----RPEALAKVKKIFVGGLKDDIEEKD 114

  Fly   276 LREIFSSCGEIDYIRCLQDGDKGCK-GVAYVCFQKPDAVGLALELNQTLLDDRPINVERYQVKKL 339
            |.|.||..|.|:....:.|.|.|.| |..:|.|:..|:...|:     :|....||..:.:|||.
Zfish   115 LTEFFSQFGMIEKSEVITDKDTGKKRGFGFVHFEDNDSADKAV-----VLKFHMINGHKVEVKKA 174

  Fly   340 GAKQVRDAA--AASAASKTSSKTKAKNQNSAG 369
            ..||...||  |.....:...:...:|||..|
Zfish   175 LTKQEIQAAGGARGGRGRGGGRGMGRNQNGFG 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	17/87 (20%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	25/71 (35%)
hnrnpa0b	NP_999871.1	RRM1_hnRNPA0	6..84	CDD:240772	18/92 (20%)
		RRM_SF	100..179	CDD:302621	29/83 (35%)
		HnRNPA1	263..294	CDD:288479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910