DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and pabpc1l

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_956133.1	Gene:	pabpc1l / 327625	ZFINID:	ZDB-GENE-030131-5836	Length:	620	Species:	Danio rerio

Alignment Length:	344	Identity:	74/344 - (21%)
Similarity:	131/344 - (38%)	Gaps:	95/344 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 PAEEASTVFVGNLPINTKRVQLVKLFQPYGLVQSIRL-------RTAGGKQLFKHKQRKVAGSLN 207
            ||...::::||:|..:.....|.:.|.|.|.:.|||:       |:.|                .
Zfish     6 PAYPLASLYVGDLHADVTEAMLYQKFSPAGQIMSIRVCRDVITRRSLG----------------Y 54

  Fly   208 AYVVLEKPEIAQQAL-ALNGSEFKENHLRVTPASMAEKFGQAKDKQPS-DKDAKRTIFVGSLKYS 270
            ||:..::|..|:.|| .:|....|...:|:          ....:.|. .|.....||:.::..|
Zfish    55 AYINFQQPADAECALDTMNYEVIKGRPIRI----------MWSQRDPGLRKSGVGNIFIKNMDES 109

  Fly   271 ATEEQLREIFSSCGEIDYIRCLQDGDKGCKGVAYVCFQKPDAVGLALE-LNQTLLDDRPINVERY 334
            ...:.|.:.||:.|.|...:.:.| :.|.||..:|.|:..:|...|:| :|..||:||.:.|..:
Zfish   110 IDNKALYDTFSAFGNILSCKVVCD-ENGSKGYGFVHFETQEAANRAIETMNGMLLNDRKVFVGHF 173

  Fly   335 QVKK-----LGAKQVR-------------DA-----------AAASAASKTSSKTKAKN------ 364
            :.:|     :|||.|.             |:           ...|....|..:.:::.
Zfish   174 KSRKEREAEMGAKAVEFTNVYIKNFGEDIDSEKLKNIFTEFGKTLSVCVMTDERGRSRGFGFVNF 238

  Fly   365 QNSAGAKKRLDKKKGKE-----------------NGSLKKEGAPTGQKKKSEYRGVKVDGIKKAK 412
            .|...|::.:.:..|||                 .|.||::.....|::...|:||.:    ..|
Zfish   239 VNHGDARRAVTEMNGKELNGRVLYVGRAQKRLERQGELKRKFEQIKQERIQRYQGVNL----YVK 299

  Fly   413 KPKKKSNDQQTALAKKIAP 431
            ......:|::  |.|:.||
Zfish   300 NLDDSIDDEK--LRKEFAP 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	21/89 (24%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	22/71 (31%)
pabpc1l	NP_956133.1	PABP-1234	11..610	CDD:130689	72/339 (21%)
		RRM1_I_PABPs	12..91	CDD:240824	21/104 (20%)
		RRM2_I_PABPs	97..172	CDD:240825	23/75 (31%)
		RRM3_I_PABPs	190..269	CDD:240826	8/78 (10%)
		RRM4_I_PABPs	293..370	CDD:240827	8/30 (27%)
		PABP	542..609	CDD:279051
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910