DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and Pabpc4

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	XP_006238860.1	Gene:	Pabpc4 / 298510	RGDID:	1305015	Length:	660	Species:	Rattus norvegicus

Alignment Length:	332	Identity:	79/332 - (23%)
Similarity:	128/332 - (38%)	Gaps:	95/332 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 STVFVGNLPINTKRVQLVKLFQPYGLVQSIRL-------RTAGGKQLFKHKQRKVAGSLNAYVVL 212
            ::::||:|..:.....|.:.|.|.|.|.|||:       |:.|                .|||..
  Rat    11 ASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG----------------YAYVNF 59

  Fly   213 EKPEIAQQAL-ALNGSEFKENHLRVTPASMAEKFGQAKDKQPS-DKDAKRTIFVGSLKYSATEEQ 275
            ::|..|::|| .:|....|...:|:          ....:.|| .|.....:|:.:|..|...:.
  Rat    60 QQPADAERALDTMNFDVIKGKPIRI----------MWSQRDPSLRKSGVGNVFIKNLDKSIDNKA 114

  Fly   276 LREIFSSCGEIDYIRCLQDGDKGCKGVAYVCFQKPDAVGLALE-LNQTLLDDRPINVERYQVKK- 338
            |.:.||:.|.|...:.:.| :.|.||.|:|.|:..:|...|:| :|..||:||.:.|.|::.:|
  Rat   115 LYDTFSAFGNILSCKVVCD-ENGSKGYAFVHFETQEAANKAIEKMNGMLLNDRKVFVGRFKSRKE 178

  Fly   339 ----LGAKQ-----------------------------------VRDAAAASAASKTSSKTKAKN 364
                ||||.                                   :||.:..|......|..|.::
  Rat   179 REAELGAKAKEFTNVYIKNFGEEVDDENLRELFSQFGKTLSVKVMRDCSGKSKGFGFVSYEKHED 243

  Fly   365 QNSA----GAKKRLDK--------KKGKENGSLKKEGAPTGQKKKSEYRGVKV------DGIKKA 411
            .|.|    ..|:...|        ||.:....||::.....|::.|.|:||.:      |.|...
  Rat   244 ANKAVEEMNGKEMSGKSIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDE 308

  Fly   412 KKPKKKS 418
            |..|:.|
  Rat   309 KLRKEFS 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	23/89 (26%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	23/71 (32%)
Pabpc4	XP_006238860.1	PABP-1234	11..640	CDD:130689	79/332 (24%)
		RRM1_I_PABPs	12..91	CDD:240824	23/104 (22%)
		RRM2_I_PABPs	97..172	CDD:240825	24/75 (32%)
		RRM3_I_PABPs	190..269	CDD:240826	9/78 (12%)
		RRM4_I_PABPs	293..370	CDD:240827	7/23 (30%)
		PABP	572..639	CDD:279051
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910