DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and rsd1

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_594422.2	Gene:	rsd1 / 2542545	PomBaseID:	SPAC19G12.07c	Length:	603	Species:	Schizosaccharomyces pombe

Alignment Length:	357	Identity:	70/357 - (19%)
Similarity:	141/357 - (39%)	Gaps:	74/357 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 PTTAPNEKPKGKVSKKA--KANANNKDEEGV---------KRIRN-PAEEAS----------TVF 158
            |.::.:.:.:.:..:::  .:.|::.|.|.:         ||.|: |.|.:|          |||
pombe   179 PYSSRHSRSRRRYEERSSRSSRAHDYDYEDLRDDDRSHERKRSRSRPRERSSKLSEEERDRRTVF 243

  Fly   159 VGNLPINTKRVQLVKLFQPYGLVQSIRLRTAGGKQLFKHKQRKVAGSLN--AYVVLEKPEIAQQA 221
            |..|.......:|...|:..|.|:..::           .:.|::|...  |||.....:..|.|
pombe   244 VSQLANRLTSRELYDFFEQAGPVRDAQI-----------VRDKISGRSKGVAYVEFCHEDSVQAA 297

  Fly   222 LALNGSEFKENHLRVTPASMAEKFGQAKDKQPSDKDAKRTI-----FVGSLKYSATEEQLREIFS 281
            :||:|.......: :...:.|||..:|::.....:.|...|     .|.::.::.|:|.::.||.
pombe   298 IALSGKRLLGLPV-IVQLTEAEKNRKAREAAELARAASAEIPFHRLCVSNIHFNLTDEDVKAIFE 361

  Fly   282 SCGEIDYIRCLQDGDKGCKGVAYVCFQKPDAVGLALE-LNQTLLDDRPINV----ERYQVKKLGA 341
            ..|:|:::...:|.....||..|:.::.|.:...||| :|...|..|.:.|    :::..:
pombe   362 PFGDIEFVHLQRDDQNRSKGFGYIQYRNPISARNALEKMNGFDLAGRNMRVCLGNDKFTTE---- 422

  Fly   342 KQVRDAAAASAASKTSSKTKAKNQNSAGAKKRLDKKKGKENGSLK-------KEGAPTGQKKKSE 399
                   ..|:..|...:|.|:.:.|         :..:.||...       :|.||....:: |
pombe   423 -------TTSSMLKRFDETLARQERS---------QPSQRNGGSSTYESQDYREAAPLSPTEE-E 470

  Fly   400 YRGVKVDGIKKAKKPKKKSNDQQTALAKKIAP 431
            .|.:..|.:.|.....:..:|....:::...|
pombe   471 SRPITRDELMKKLARSEDISDNSKLVSEPEPP 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	20/93 (22%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	20/80 (25%)
rsd1	NP_594422.2	RRM1_RBM39_like	241..313	CDD:240729	19/83 (23%)
		RRM2_RBM23_RBM39	342..413	CDD:240730	18/70 (26%)
		RBM39linker	476..523	CDD:292157	4/27 (15%)
		RRM3_RBM39_like	505..589	CDD:240731
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910