DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and pabp

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_593377.1	Gene:	pabp / 2541505	PomBaseID:	SPAC57A7.04c	Length:	653	Species:	Schizosaccharomyces pombe

Alignment Length:	385	Identity:	83/385 - (21%)
Similarity:	139/385 - (36%)	Gaps:	83/385 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 LKKQQNKLAPKEIKTEPEAQVKVESKATKKEKVEKEPTTAPNEKPKGKVSKKAKANANNKDEEGV 144
            ||||.:.....::.|..||   ||| :||:|......|....||...:....|:.:.:.......
pombe     6 LKKQADAAVESDVNTNNEA---VES-STKEESSNTPSTETQPEKKAEEPEAAAEPSESTSTPTNA 66

  Fly   145 KRIRNPAEEAST---VFVGNLPINTKRVQLVKLFQPYGLVQSIRL-RTAGGKQLFKHKQRKVAGS 205
            ..:..|:..|.|   ::||.|..:.....|.:||...|.|.|||: |.|..::...:
pombe    67 SSVATPSGTAPTSASLYVGELDPSVTEAMLFELFNSIGPVASIRVCRDAVTRRSLGY-------- 123

  Fly   206 LNAYVVLEKPEIAQQAL-ALNGSEFKENHLRVTPASMAEKFGQAKDKQPS-DKDAKRTIFVGSLK 268
              |||.....|..::|| .||.:..|....|:          ....:.|| .|.....:|:.:|.
pombe   124 --AYVNFHNMEDGEKALDELNYTLIKGRPCRI----------MWSQRDPSLRKMGTGNVFIKNLD 176

  Fly   269 YSATEEQLREIFSSCGEIDYIRCLQDGDKGCKGVAYVCFQKPDAVGLALE-LNQTLLDDRPI--- 329
            .:...:.|.:.||:.|:|...:...|.....||..:|.|...::...|:| :|..||:|:.:
pombe   177 PAIDNKALHDTFSAFGKILSCKVAVDELGNAKGYGFVHFDSVESANAAIEHVNGMLLNDKKVYVG 241

  Fly   330 -----------------NVERYQVKKLGA----KQVRDAAAASAASKTSSKTKAKNQNSAG---- 369
                             |.....:|.|..    ::..|.........:.|..|.:|....|
pombe   242 HHVSRRERQSKVEALKANFTNVYIKNLDTEITEQEFSDLFGQFGEITSLSLVKDQNDKPRGFGFV 306

  Fly   370 -------AKKRLD-----------------KKKGKENGSLKKEGAPTGQKKKSEYRGVKV 405
                   |:|.:|                 :||.:....|:|.......:|.::|:||.:
pombe   307 NYANHECAQKAVDELNDKEYKGKKLYVGRAQKKHEREEELRKRYEQMKLEKMNKYQGVNL 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	24/86 (28%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	19/91 (21%)
pabp	NP_593377.1	PABP-1234	80..642	CDD:130689	63/307 (21%)
		RRM1_I_PABPs	81..160	CDD:240824	23/98 (23%)
		RRM2_I_PABPs	166..242	CDD:240825	18/75 (24%)
		RRM3_I_PABPs	260..339	CDD:240826	10/78 (13%)
		RRM4_I_PABPs	363..441	CDD:240827	2/4 (50%)
		PolyA	581..644	CDD:197769
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910