DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and Tial1

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_033409.1	Gene:	Tial1 / 21843	MGIID:	107913	Length:	392	Species:	Mus musculus

Alignment Length:	241	Identity:	57/241 - (23%)
Similarity:	93/241 - (38%)	Gaps:	61/241 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 TVFVGNLPINTKRVQLVKLFQPYGLVQSIRLRTAGGKQLFKHKQRKVAGSLNAYVV--------- 211
            |::||||..:...|.:::||...|..:|.::.|.      :...|:|..|:...|:
Mouse    10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITE------QPDSRRVNSSVGFSVLQHTSNDPYC 68

  Fly   212 ----LEKPEIAQQALALNGSEFKENHLRV----TPASMAEKFGQAKDKQPSDKDAKRTIFVGSLK 268
                .|..:.|....|:||.:.....::|    ||:|           |..|......:|||.|.
Mouse    69 FVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSS-----------QKKDTSNHFHVFVGDLS 122

  Fly   269 YSATEEQLREIFSSCGEIDYIRCLQDGDKG-CKGVAYVCF-QKPDAVGLALELNQTLLDDRPINV 331
            ...|.|.::..|:..|:|...|.::|...| .||..:|.| .|.||....:.:..
Mouse   123 PEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGG---------- 177

  Fly   332 ERYQVKKLGAKQVRD--AAAASAASKTSSKTKAK--------NQNS 367
                 :.||.:|:|.  |.....|.|::.:|..|        ||:|
Mouse   178 -----QWLGGRQIRTNWATRKPPAPKSTQETNTKQLRFEDVVNQSS 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	21/97 (22%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	19/72 (26%)
Tial1	NP_033409.1	RRM1_TIAR	10..107	CDD:410028	24/113 (21%)
		RRM2_TIAR	113..192	CDD:410029	24/93 (26%)
		RRM3_TIAR	222..294	CDD:241064
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	363..392
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910